临床药师在神经外科开展抗菌药物管理的效果分析

Exploration and evaluation of pharmacists-lead antibiotic pharmaceutical care of neurosurgery

目的探讨临床药师主导的抗菌药物精细化管理在神经外科术后抗感染治疗中发挥的作用,并对神经外科患者术后感染的影响因素进行分析。方法纳入2019年神经外科收入的手术患者,对临床药师干预前后抗感染治疗药物使用情况进行分析。结果开展临床药师干预前,神经外科术后感染抗菌药物治疗总的合理率为88.89%。不合理原因主要为无适应证用药和使用时间过长,分别占比42.85%和28.57%;干预后,治疗用药总的合理率从干预前(3个月)的77.78%提升到干预后(9个月)的92.86%。结论神经外科患者术后感染复杂,专科临床药师通过开展基于床旁的药学服务,有助于提高抗菌药物的规范使用。

Objective To explore the role of clinical pharmacists in rational drug use of infection treatment after neurosurgery and to analyze the influencing factors of infection after neurosurgery.Methods Patients enrolled in the neurosurgery ward in 2019 were analysed for the use of anti-infective drugs before and after the intervention of clinical pharmacists.Results The total rationality rate is 88.89%.The main reasons for unreasonable antibacterial treatment of postoperative neurosurgery infection are the use of drugs without indications(42.85%)and overlong using period(28.57%).After clinical pharmacists’intervention,the total reasonable treatment rate increased from 77.78%to 92.86%.Conclusion Treatment of postoperative infection in neurosurgery is complex.Bedside based pharmaceutical care helps to improve the standard use of antibacterial drugs.