透析及非透析终末期肾脏病患者血管钙化情况和影响因素分析

Clinical characteristics and influencing factors of vascular calcification in dialysis and non-dialysis patients with end stage renal disease

目的:评估透析及非透析终末期肾脏病(ESRD)患者血管钙化情况并探讨其影响因素。方法:纳入我院2019年12月至2020年12月病情稳定的ESRD患者191例,分为透析组74例、非透析组117例,比较两组患者的血管钙化发生率及钙化严重程度,分析血管钙化的影响因素。结果:透析组血管钙化发生率(56.8%)显著高于非透析组(41.9%)。logistic回归分析结果表明高龄和空腹血糖升高是非透析ESRD患者血管钙化的危险因素,高龄和高血压是透析ESRD患者发生血管钙化的危险因素(P<0.05)。结论:透析和非透析ESRD患者血管钙化的特征和影响因素存在差异,应该针对其特点进一步优化管理,实现个体化管控。

Objective:To evaluate the vascular calcification in dialysis and non-dialysis patients with end-stage renal disease(ESRD),and to explore its influencing factors.Methods:191 ESRD patients with stable disease in our hospital from September 2019 to September 2020 were divided into dialysis group(n=74)and non-dialysis group(n=117).Results:The incidence of vascular calcification in dialysis group(56.8%)was significantly higher than that in non-dialysis group(41.9%).The results of logistic regression analysis indicated that advanced age and fasting blood glucose were the risk factors of vascular calcification in non-dialysis ESRD patients,and advanced age and hypertension were the risk factors of vascular calcification in dialysis ESRD patients(P<0.05).Conclusion:There are differences in the characteristics and influencing factors of vascular calcification between dialysis and non-dialysis ESRD patients.Management should be further optimized according to their characteristics to achieve individualized management and control.