食品中金刚烷胺的危害、检测方法和残留风险研究进展

Research progress for hazards,detection methods and residual risk of amantadine in food

金刚烷胺是一种抗病毒药物,能够改善帕金森氏症状和预防流感病毒。因其具有价格低廉和良好的抗流感病毒效果等特点常被用于防治禽流感。但过量使用金刚烷胺,会使其在环境和食品中产生残留,导致病毒产生耐药性,并可通过食物链传递到人体,对人体健康造成潜在危害,具有一定的生态风险和食品安全风险。尽管各国开始限制金刚烷胺的使用,但目前市场上部分食品中,仍能检出金刚烷胺残留。本研究对食品中金刚烷胺的危害、仪器分析检测方法和残留风险进行分析,为开展更广泛的动植物中金刚烷胺残留量测定及其造成的食品和生态安全风险评价提供参考。

Amantadine is an antiviral drug,which can improve the symptoms of Parkinson's disease and prevent influenza virus.Because of its low price and good anti-influenza Virus effect,it is often used to prevent and control avian influenza.However,excessive use of amantadine can produce residues in the environment and food,along with drug resistance of viruses,and pass through food chain to the human body with potential hazard to human health,which posing certain ecological risk and food safety risk.Although various countries have started to restrict the use of amantadine,the residues of amantadine can still be detected in some foods on the market.In this study,the hazard,instrumental analysis detection methods,and residual risks of amantadine in food were reviewed,in order to provide references for the detection of amantadine residues in animals and plants,as well as the assessment of food and ecological safety risks brought by amantadine.