持续性防损伤联合疼痛干预在多发性骨髓瘤患者院内外疼痛控制的作用

The effect of continuous injury prevention combined with pain intervention on pain control in and out of hospital in patients with multiple myeloma

目的探讨持续性防损伤联合疼痛干预在多发性骨髓瘤患者院内外疼痛控制的作用。方法选取2018年7月至2020年7月该院收治的多发性骨髓瘤患者112例,随机分为对照组和观察组,各56例。对照组采用常规干预,观察组采用持续性防损伤联合疼痛干预。比较两组不良事件发生率、干预前后疼痛程度及生活质量变化。结果观察组不良事件发生率低于对照组,差异有统计学意义(P<0.05);观察组干预3个月、6个月后疼痛程度轻于对照组,差异有统计学意义(P<0.05);观察组干预6个月后功能性指标、总体健康评分均高于对照组,症状性指标、食欲丧失及失眠评分均低于对照组,差异有统计学意义(P<0.05);呼吸困难、便秘、腹泻、经济困难评分与对照组相比无明显差异。结论持续性防损伤联合疼痛干预应用于多发性骨髓瘤患者可有效缓解其疼痛程度,提高生活质量,同时减少不良事件发生。

Objective To explore the effect of continuous injury prevention combined with pain intervention applied to pain control in and out of hospital in patients with multiple myeloma.Methods A total of 112 patients with multiple myeloma admitted to this hospital from July 2018 to July 2020 were selected and randomly divided into two groups with 56 cases in each group.The control group used conventional intervention,and the observation group used continuous injury prevention combined with pain intervention.The incidence of adverse events,pain degree before and after intervention and changes in quality of life were compared between the two groups.Results The incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The pain degree of the observation group was lighter than that of the control group 3 months and 6 months after intervention(P<0.05).The functional indexes and overall health scores of the observation group were higher than those of the control group after 6 months of intervention.The symptomatic indicators,appetite loss and insomnia scores were all lower than those of the control group,and the differences were statistically significant(P<0.05).There were no significant differences in dyspnea,constipation,diarrhea and economic hardship scores between the two groups.Conclusions Continuous injury prevention combined with pain intervention in patients with multiple myeloma can effectively relieve their pain,improve the quality of life,and reduce the occurrence of adverse events.