高危型人乳头瘤病毒感染者心理健康状况调查及影响因素分析

Investigation of psychological health status of patients with high-risk human papillomavirus infection and its influencing factors analysis

目的:调查高危型人乳头瘤病毒(HR-HPV)感染者心理健康状况并分析影响因素。方法:选取本院2019年7月-2021年11月收治的148例HR-HPV感染者,通过调查问卷分析基线资料,采用焦虑自评表(SAS),抑郁自评量表(SDS)评估患者心理健康状况并分析可能影响因素。结果:148例HR-HPV感染者中焦虑阳性率80.4%,抑郁阳性率77.7%;分析患者临床资料发现,家人支持、感染途径、怀孕计划、性生活质量、对HPV的了解情况是影响HR-HPV感染者心理健康状况的单因素;多因素logistics回归分析显示,家人支持不足(OR_(焦虑)=3.438,95%CI_(焦虑)2.144~5.514;OR_(抑郁)=2.651,95%CI_(抑郁)1.753~4.009)、有妊娠计划(OR_(焦虑)=3.721,95%CI_(焦虑)1.580~8.763;OR_(抑郁)=3.080,95%CI_(抑郁)1.109~8.552)、性生活质量差(OR_(焦虑)=1.556,95%CI_(焦虑)1.098~2.205;OR_(抑郁)=1.664,95%CI_(抑郁)1.056~2.560)、对HPV了解缺乏(OR_(焦虑)=1.853,95%CI_(焦虑)1.073~3.202;OR_(抑郁)=1.781,95%CI_(抑郁)1.108~2.861)是HR-HPV感染者产生焦虑、抑郁心理的影响因素(P>0.05)。结论:HR-HPV感染者焦虑、抑郁情绪发生比例较高,其发生与患者的家人支持程度、妊娠计划、性生活质量及对HPV的了解情况等不足有关,提示临床治疗过程中应重视患者心理健康干预。

Objective: To explore the psychological health status of patients with high-risk human papillomavirus(HR-HPV) infection, and to analyze the influencing factors of the psychological health status of the patients. Methods: 148 patients with HR-HPV infection were selected in the study between July 2019 and November 2021. The baseline data of the patients were analyzed by questionnaire. The psychological health status of the patients was assessed by Self-rating Anxiety Scale(SAS) and Self-rating Depression Scale(SDS), and the psychological status-related factors were analyzed. Results: The positive rates of anxiety and depression of 148 patients with HR-HPV infection were 80.4% and 77.7%. Analysis of clinical data of these patients showed that family support, infection route, pregnancy plan, sexual life quality, or knowledge of HPV was the single factor affecting the mental health status of the patients with HR-HPV infection. Multivariate logistic regression analysis showed that insufficient family support(OR of anxiety 3.438, 95%CI 2.144-5.514, and OR of depression 2.651, 95%CI 1.753-4.009), pregnancy plan(OR of anxiety 3.721, 95% CI1.580-8.763, and OR of depression 3.080, 95%CI 1.109-8.552), poor sexual quality(OR of anxiety 1.556, 95%CI 1.098-2.205, and OR of depression 1.664, 95%CI 1.056-2.560), lack of knowledge about HPV(OR of anxiety 1.853, 95%CI 1.073-3.202, and OR of depression 1.781, 95%CI 1.108-2.861) were the influential factors for the anxiety and depression of the patients with HR-HPV infection(P<0.05). Conclusion: The incidences of anxiety and depression of the patients with HR-HPV infection are higher, which are related to their lack of family support, pregnancy plan,sexual life quality,or understanding of HPV.So that mental health intervention of the patients should be paid attention to in the process of clinical treatment.