梅尼埃病中医证型及证素分布规律文献研究

Literature Study on Distribution Regularity of Syndrome Type and Syndrome Element of Traditional Chinese Medicine in Meniere’s Disease

目的:探讨梅尼埃病的中医证型、证素分布规律,为临床辨治提供参考。方法:检索中国知网(CNKI)、万方数据知识服务平台(WF)、维普期刊资源整合服务平台(VIP)、中国生物医学文献数据库在2020年3月24日之前收录的与梅尼埃病中医证型相关的文献,筛选后提取证候要素,统计各证型、证素出现的频数及相关证型、证素的病例数及构成比。结果:共纳入文献22篇,纳入病例数1585例,纳入病例年龄15岁至95岁。梅尼埃病共有证型28种,频数最高的6种证型为肝阳上亢、气血两虚、痰湿中阻、痰浊中阻、风阳上扰、髓海不足。病例数量最多的前5种证型为痰湿中阻、痰浊中阻、肝阳上亢、气血两虚、痰湿夹瘀。纳入病例中,实证的病例数最多。实证性质的证型有14种,频数最多的为痰湿中阻证和痰浊中阻证;虚证性质的证型种类有9种,频数最多的为气血两虚证;虚实夹杂性质的证型种类有5种,频数最多的为肝阳上亢证。梅尼埃病证素共有12种,分别为湿、瘀、痰、寒、热(火)、风、阳亢、精虚、气虚、血虚、阴虚、阳虚。病位证素共有3种,分别为肝、脾、肾。结论:梅尼埃病基本病机为本虚标实,病理因素主要是痰,病位在肝、肾、脾。临床辨证论治需注意虚实病性,要注重祛痰,可从肝着手兼顾肾、脾。

Objective:To explore the distribution regularity of traditional Chinese medicine(TCM)syndrome type and syndrome element of Meniere’s disease,and to provide reference for clinical syndrome differentiation and treatment.Methods:TCM syndrome related literature of Meniere’s disease was collected by China National Knowledge Infrastructure(CNKI),Wanfang Database Knowledge Service Platform(WF),Weipu Journal Resource Integration Service Platform(VIP)and China Biomedical Literature Database before March 24th,2020,and the syndrome elements were extracted after screening,and the frequency,and the case number and composition ratio of each syndrome type and syndrome element were counted.Results:Total 22 articles were included,including 1585 cases aged from 15 to 95.There are 28 syndrome types of Meniere’s disease,and 6 types with the highest frequency are hyperactivity of liver yang,deficiency of both qi and blood,obstruction of phlegm dampness,obstruction of phlegm turbidity,disturbance of wind yang and insufficiency of marrow sea.Top five syndrome types with the largest number of cases are obstruction of phlegm dampness,obstruction of phlegm turbidity,hyperactivity of liver yang,deficiency of both qi and blood,phlegm dampness with blood stasis.Among the cases included,the number of excess cases is the largest.There are 14 excess syndrome types,and the most frequent ones are obstruction of phlegm dampness and obstruction of phlegm turbidity.There are 9 types of deficiency syndrome,and the most frequent one is deficiency of both qi and blood.There are 5 types of deficiency and excess in complexity syndrome type,and the most frequent one is hyperactivity of liver yang.There are total 12 kinds of syndrome elements in Meniere’s disease,which are dampness,blood stasis,phlegm,cold,heat(fire),wind,yang hyperactivity,essence deficiency,qi deficiency,blood deficiency,yin deficiency and yang deficiency.There are 3 kinds of syndrome elements in disease location,which are liver,spleen and kidney.Conclusions:The basic pathogenesis of Meniere’s disease is deficiency in root and excess in branch.The pathological factor is mainly phlegm.The disease is located in liver,kidney and spleen.In clinical treatment based on syndrome differentiation,attention should be paid to the feature of deficiency and excess and expelling phlegm,it is recommended to focus on treating the liver and taking into account the kidney and spleen.