2017年广西肿瘤登记地区恶性肿瘤流行特征及疾病负担分析

Epidemiological characteristics and disease burden of cancer in Guangxi cancer registration areas,2017

目的分析2017年广西肿瘤登记地区恶性肿瘤的流行特征及其造成的疾病负担,为广西恶性肿瘤防治提供参考。方法根据2017年广西33个肿瘤登记地区上报的肿瘤发病和死亡数据,计算发病率、死亡率及其中国人口和世界人口标化率(简称中标发病率/死亡率和世标发病率/死亡率)等指标分析恶性肿瘤的流行特征;采用伤残损失寿命年(years of lived with disability,YLDs)、过早死亡损失寿命年(years of life lost,YLLs)和伤残调整寿命年(disability⁃adjusted life years,DALYs)等指标评价恶性肿瘤疾病负担。结果2017年广西肿瘤登记地区恶性肿瘤共报告新发病例34105例,粗发病率为243.67/10万,中标发病率为201.71/10万,世标发病率为196.51/10万;共报告死亡例数20709例,粗死亡率为147.96/10万,中标死亡率为117.81/10万,世标死亡率为116.26/10万。恶性肿瘤发病前10位分别是肺癌、肝癌、女性乳腺癌、结直肠癌、子宫颈癌、胃癌、鼻咽癌、子宫体癌、前列腺癌和卵巢癌,占全部恶性肿瘤发病的74.0%;死亡前10位分别为肝癌、肺癌、结直肠癌、胃癌、女性乳腺癌、子宫颈癌、鼻咽癌、食管癌、白血病和脑癌,占全部恶性肿瘤死亡的82.0%。2017年广西恶性肿瘤合计损失的DALYs为301738.20人年,DALYs率为2155.86/10万人年,DALYs率前10位癌种分别为肝癌、肺癌、女性乳腺癌、结直肠癌、胃癌、子宫颈癌、鼻咽癌、白血病、脑癌和食管癌。结论2017年广西恶性肿瘤发病率、死亡率和DALYs率均处较高水平,肺癌、肝癌、结直肠癌、鼻咽癌、女性乳腺癌、子宫颈癌等是广西重点防治的恶性肿瘤。

Objective To analyze the epidemiological characteristics and disease burden of malignant tumors in Guangxi cancer registration areas in 2017,and to provide evidence for prevention and treatment of malignant tumors.Methods According to the tumor incidence and death data reported by 33 cancer registration areas in Guangxi in 2017,the incidence,mortality and age⁃standardized rate by Chinese standard population(ASRC)and world standard population(ASRW)were calculated to analyze the epidemiological characteristics of malignant tumors.The years of lived with disability(YLDs),years of life lost(YLLs)and disability⁃adjusted life years(DALYs)related to cancer were collated to assess the disease burden of malignant tumors.Results In 2017,a total of 34,105 new cases of malignant tumors were reported in Guangxi cancer registration areas,with a crude incidence of 243.67/105,ASRC of 201.71/105 and ASRW of 196.51/105.A total of 20,709 deaths were reported,with a crude mortality rates of 147.96/105,ASRC of 117.81/105 and ASRW of 116.26/105.The cancer of the lung,liver,female breast,colorectum,cervix,stomach,nasopharynx,uterus,prostate and ovary were the top ten for malignant tumors incidence,accounting for 74.0%of total cancer cases.The cancer of liver,lung,colorectum,stomach,female breast,cervix,nasopharynx,esophagus,leukemia and brain were the ten leading causes of cancer deaths,accounting for 82.0%of total cancer deaths.Cancers resulted in 301,738.20 DALYs in Guangxi in 2017,the DALYs rates were 2,155.86 DALYs per 105 persons.The top 10 cancers in DALYs rate were the cancers of liver,lung,female breast,colorectum,stomach,cervix,nasopharynx,leukemia,brain,and esophagus.Conclusions In 2017,the incidence,mortality,and DALYs rates of malignant tumors in Guangxi were all at a high level.The lung cancer,liver cancer,colorectum cancer,nasopharynx cancer,female breast cancer and cervix cancer are the major malignant tumor for prevention and treatment in Guangxi.