摘要
β-抑制蛋白2是抑制蛋白家族成员,主要通过G蛋白偶联受体(G protein-coupled receptor,GPCR)信号通路传导以及参与多种炎症信号通路在炎症性疾病中发挥重要作用。本文回顾了β-抑制蛋白2的结构功能,并就β-抑制蛋白2在炎症性疾病中的作用机制进行综述。
β-arrestin 2 belongs to the inhibitory protein family which plays a pivotal role in inflammatory diseases,and it involves in inflammatory diseases through the G protein-coupled receptor(GPCR)signal transduction pathway and its participation in various signaling pathways.In this paper we review the function ofβ-arrestin 2 and summarize the mechanism ofβ-arrestin 2 in inflammatory diseases.
作者
冯梅婷
罗礼君
FENG Meiting;LUO Lijun(Department of Periodontics,School of Stomalology,Tongji Universily,Shanghai Engineering Research Center of Tooth Restoration and Regeneration Shanghai 200072,China)
出处
《口腔医学》
CAS
2022年第6期540-544,共5页
Stomatology
基金
国家自然科学基金面上项目(82071123)。
