轮状病毒肠炎患儿发生心肌损害的相关因素分析

Related factors of myocardial damage in children with rotavirus enteritis

目的探讨轮状病毒肠炎患儿发生心肌损害的相关因素。方法抽取2019年1月至2021年1月郑州市中心医院收治的141例轮状病毒肠炎患儿作为研究对象,统计心肌损害发生情况;由研究人员设计基线资料调查表,询问并记录患儿基线资料,比较发生与未发生心肌损害患儿的基线资料,并采用Logistic回归分析法分析轮状病毒肠炎患儿发生心肌损害的相关因素。结果141例患儿中发生心肌损害126例,未发生心肌损害15例;发生组患儿性别、年龄、轮状病毒肠炎病程、腹泻次数、发热、呼吸道症状、白细胞计数、血红蛋白、血钠水平与未发生组比较差异未见统计学意义(P>0.05);发生组患儿呕吐次数高于未发生组,中重度脱水、代谢性酸中毒占比高于未发生组,血钾水平低于未发生组(P<0.05)。经Logistic回归分析结果显示,呕吐次数多、中重度脱水、代谢性酸中毒是轮状病毒肠炎患儿发生心肌损害的危险因素(OR>1,P<0.05);血钾水平高是轮状病毒肠炎患儿发生心肌损害的保护因素(OR<1,P<0.05)。结论呕吐次数多、中重度脱水、代谢性酸中毒、血钾水平是轮状病毒肠炎患儿发生心肌损害的相关因素。

Objective To investigate the related factors of myocardial damage in children with rotavirus enteritis.Methods A total of 141 children with rotavirus enteritis treated in Zhengzhou Central Hospital from January 2019 to January 2021 were selected as the research subjects.The occurrence of myocardial damage was counted;the baseline data questionnaire was designed by researchers to request and record the baseline data of children,and then the baseline data of children with and without myocardial damage were compared.Logistic regression analysis was used to analyze the related factors of myocardial damage in children with rotavirus enteritis.Results Among the 141 children,126 cases had myocardial damage,and 15 cases did not have myocardial damage.There was no significant difference in gender,age,course of rotavirus enteritis,frequency of diarrhea,fever,respiratory symptoms,white blood cell count,hemoglobin and blood sodium level between the occurrence group and the non occurrence group(P>0.05).The frequency of vomiting in the occurrence group was higher than that in the non occurrence group,the proportion of moderate and severe dehydration and metabolic acidosis was higher than that in the non occurrence group,and the blood potassium level was lower than that in the non occurrence group(P<0.05).The results of Logistic regression analysis showed that more times of vomiting,moderate and severe dehydration,and metabolic acidosis were the risk factors of myocardial damage in children with rotavirus enteritis(OR>1,P<0.05);high serum potassium level was a protective factor for myocardial damage in children with rotavirus enteritis(OR<1,P<0.05).Conclusions The more times of vomiting,moderate and severe dehydration,metabolic acidosis and blood potassium level are the related factors of myocardial damage in children with rotavirus enteritis.