芪参益气滴丸对PCI术后CHD患者三个方面的影响

Effects of Qishen Yiqi dropping pills on three aspects of patients with CHD after PCI

目的探讨芪参益气滴丸对冠心病(CHD)患者经皮冠状动脉介入术(PCI)术后的应用及其对心功能、体力活动及主要不良心血管事件(MACE)发生率的影响。方法选取2019年10月~2020年11月在湖北民族大学附属民大医院接受PCI治疗的84例CHD术后患者,随机数字表法将其分为对照组和研究组各42例,对照组给予西医常规治疗,研究组在对照组基础上联合芪参益气滴丸治疗,比较两组临床疗效、心功能、中医证候评分、6 min步行距离、体力活动水平以及MACE发生情况。结果研究组临床治疗总有效率92.86%高于对照组的76.19%(P<0.05);治疗后研究组心搏量、左室射血分数、左室收缩末期内径、左室舒张末期内径各心功能指标以及中医证候评分、6 min步行距离改善情况均优于对照组(P<0.01);治疗后研究组高、中水平体力活动者比例高于对照组(P<0.05);研究组MACE发生率9.52%明显低于对照组的28.57%(P<0.05)。结论对CHD患者PCI术后给予芪参益气滴丸治疗效果明显,可提升患者心搏量及射血分数,改善其其心功能,并能促进患者体力活动,降低MACE发生率,有利于患者恢复。

AIM To investigate the application of Qishen Yiqi dropping pills in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI),and its influence on cardiac functions,physical activity and the incidence of major adverse cardiovascular events(MACE).METHODS A total of 84 patients with CHD treated by PCI in Minda Hospital Affiliated to Hubei University for Nationalities were selected between October 2019 and November 2020.Using random number table method,the patients were divided into control group and study group,with 42 patients in each group.The control group was treated with conventional western medicines and the study group was treated with Qishen Yiqi dropping pills based on the treatment of control group.Clinical effects,cardiac functions,TCM syndrome scores,6-min walking distance,physical activity level and the occurrence of MACE were compared between the two groups.RESULTS The total effective rate of clinical treatment in the study group was 92.86%,higher than 76.19%in the control group(P<0.05).After treatment,stroke volume,left ventricular ejection fraction,left ventricular end-systolic diameter,left ventricular enddiastolic diameter,TCM syndrome scores and 6-min walking distance in the study group were better than those in the control group(P<0.01).After treatment,the proportions of patients with high-level and medium-level physical activities in the study group were higher than those in the control group(P<0.05).The incidence of MACE in the study group was 9.52%,significantly lower than 28.57%in the control group(P<0.05).CONCLUSION Qishen Yiqi dropping pills increase the stroke volume and ejection fraction,improve cardiac functions,promote physical activity and reduce the incidence of MACE in CHD patients after PCI,which are conducive to the patients’recovery.