不同年龄段心外膜脂肪组织体积及其相关值与冠心病发生的相关性研究

Correlation study between epicardial adipose tissue volume and its relative values and the occurrence of coronary atherosclerotic heart disease in different age groups

目的:探讨冠状动脉CT血管成像(CCTA)测量的成人不同年龄段心外膜脂肪组织体积(EATV)及左右房室沟处脂肪厚度与冠状动脉粥样硬化性心脏病(冠心病)的相关性。方法:回顾性分析接受CCTA检查的患者292例,根据CCTA结果分为冠心病组和对照组,分析不同年龄段的EATV及其相关值与冠心病发生的相关性。结果:冠心病组与对照组年龄、EATV差异均有统计学意义(均P<0.05);随EATV增加,发生冠心病的风险增加。不同年龄段左房室沟处脂肪厚度总体均数差异有统计学意义(P<0.05)。在45~59岁年龄段,冠心病组和对照组EATV、右房室沟脂肪厚度差异均有统计学意义(均P<0.05)。结论:EATV可预测冠心病的发生。45岁以上不同年龄段左房室沟处脂肪厚度存在差异,提示左房室沟处脂肪厚度在不同年龄段体检筛查中可能存在潜在的预测价值;45~59岁年龄段EATV、右房室沟处脂肪厚度可能对冠心病的发生有更好的预测价值。

Objective:To investigate the correlation between epicardial adipose tissue volume(EATV)and fat thickness in the left and right atrioventricular sulcus and coronary atherosclerotic heart disease(CAD)measured by coronary CTA(CCTA).Methods:A total of 292 patients who underwent cardiac CCTA examination were retrospectively enrolled and divided into a CAD group and a control group according to the CCTA results.The correlation between EATV and CAD in different age groups was analysed and discussed.Results:There were statistically significant differences in age(P<0.05)and EATV between the CAD group and the control group.The total mean thickness of fat in the left atrioventricular sulcus of adults in different age groups was significantly different(P<0.05).There were statistically significant differences in EATV and right atrioventricular sulcus thickness between the CAD group and the control group in the 45~59 years of age group(both P<0.05).Conclusions:EATV can predict the occurrence of CAD.The fat thickness of the left atrioventricular sulcus was different among different age groups over 45 years old.EATV and fat thickness in the right atrioventricular sulcus at 45~59 years of age may have better predictive value for CAD.