摘要
目的 观察丁螺环酮联合米氮平与正念认知疗法治疗对高血压合并抑郁症患者血压、17项汉密尔顿抑郁量表(HAMD17)评分的影响。方法 选取高血压合并抑郁症患者112例,随机分为对照组和观察组各56例。对照组给予药物治疗(丁螺环酮+米氮平),观察组在对照组基础上给予正念认知疗法,比较两组血压变化情况、HAMD17评分、不良反应发生率以及生活质量。结果 观察组干预后血压改善优于对照组,HAMD17评分和不良反应发生率低于对照组(P<0.05);观察组干预后生活质量高于对照组(P<0.05)。结论 丁螺环酮联合米氮平与正念认知疗法可有效改善高血压合并抑郁症患者血压变化情况,减轻抑郁症状,降低不良反应发生率,改善生活质量。
Aim To study the effects of buspirone combined with mirtazapine and mindfulness cognitive therapy on blood pressure and 17 item Hamilton Depression Scale(HAMD17)score in patients with hypertension complicated with depression.Methods 112 patients with hypertension complicated with depression were randomly divided into two groups,56 cases in each group.The control group was given drug treatment(buspirone+mirtazapine),and the observa-tion group was given mindfulness cognitive therapy on the basis of the control group.The changes of blood pressure,HAMD17 score,incidence of adverse reactions and quality of life of the two groups were compared.Results The blood pressure changes of the observation group after intervention were better than those of the control group(P<0.05);the HAMD17 score of the observation group after intervention was lower than that of the control group(P<0.05);the inci-dence of adverse reactions in the observation group was lower than that of the control group(P<0.05);The quality of life of the observation group after intervention was higher than that of the control group(P<0.05).Conclusion The ap-plication of mindfulness cognitive therapy for elderly patients with hypertension and depression can effectively improve their blood pressure changes,reduce their depressive symptoms,and significantly reduce the incidence of adverse reactions in patients and improve their quality of life.
作者
孙丽丽
胡伟
范秋瑾
朱锋利
SUN Lili;HU Wei;FAN Qiujin;ZHU Fengli(Fuyang Third People's Hospital,Fuyang 236000,Anhui,China)
出处
《中南医学科学杂志》
CAS
2022年第5期758-761,共4页
Medical Science Journal of Central South China
关键词
丁螺环酮
米氮平
正念认知疗法
高血压
抑郁症
生活质量
buspirone
mirtazapine
mindfulness cognitive therapy
hypertension
depression
quality of life