比较右佐匹克隆片与艾司唑仑片治疗戒毒人员睡眠障碍的临床疗效及对睡眠质量的影响

To Compare the Clinical Efficacy of Dexzopicron Tablets and Esazolam Tablets in the Treatment of Sleep Disorders in Drug Addicts and the Effects on Sleep Quality

目的探讨在戒毒人员睡眠障碍治疗中右佐匹克隆片与艾司唑仑片对临床疗效及对睡眠质量的影响。方法选取2019年1月-2021年在2月在我院接受治疗的60例汕尾市强制隔离戒毒所学员作为研究对象,根据随机数字表法将患者分为两组,分别为观察组(n=30)与对照组(n=30),对照组使用艾司唑仑片治疗,观察组使用右佐匹克隆片治疗,对两组临床疗效、心理状态及对睡眠质量进行比较。结果观察组治疗总有效率与对照组相比明显更高(P<0.05);治疗后,两组汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评分明显降低(P<0.05),观察组HAMA、HAMD评分较对照组明显更低(P<0.05);治疗后,两组睡眠状况问卷自评量表(SRSS)评分较治疗前明显降低(P<0.05),匹兹堡睡眠质量指数量表(PSQI)评分较治疗前明显提高(P<0.05),观察组SRSS评分明显低于对照组(P<0.05),PSQI评分明显高于对照组(P<0.05)。结论将右佐匹克隆片应用于戒毒人员睡眠障碍患者中可促进临床疗效的提高,有效改善患者心理状态,提高睡眠质量。

Objective To investigate the effects of dexzopicclone and estazolam tablets on the clinical efficacy and sleep quality in the treatment of sleep disorders in drug addicts.Methods A total of 60 patients from Shanwei compulsory isolation drug treatment center who were treated in our hospital from January 2019 to February 2021 were selected as the research objects.According to the random number table method,the patients were divided into two groups:the observation group(n=30)and the control group(n=30).The control group was treated with estazolam tablet,and the observation group was treated with dexzopicron tablet.The clinical efficacy,psychological state and sleep quality of the two groups were compared.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,the scores of Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)in the two groups were significantly decreased(P<0.05),and the scores of HAMA and HAMD in the observation group were significantly lower than those in the control group(P<0.05).After treatment,the SRSS score of the two groups was significantly lower than that before treatment(P<0.05),and the Pittsburgh Sleep Quality Index(PSQI)score was significantly higher than that before treatment(P<0.05),and the SRSS score of the observation group was significantly lower than that of the control group(P<0.05).PSQI score was significantly higher than that of control group(P<0.05).Conclusion The application of dexzopicron tablet in patients with sleep disorders in drug addicts can promote the improvement of clinical efficacy,effectively improve the psychological state of patients,and improve the quality of sleep.