保妇康栓联合甲硝唑治疗慢性宫颈炎对患者的临床疗效观察

Treatment of Chronic Cervicitis with Maternal and Child Health Protection and Metronidazole: a Case Report

目的 以慢性宫颈炎患者作为研究对象,应用保妇康栓联合甲硝唑治疗方案,观察该项治疗方案临床疗效。方法 选择广东东莞友华医院2019年7月-2020年7月收治的80例慢性宫颈炎患者作为研究对象,基于慢性宫颈炎患者用药内容差异平均分组,每组各40例,对照组单纯应用甲硝唑治疗,研究组应用甲硝唑联合保妇康栓,观察两组治疗有效率、不良反应发生率和不同阶段血清白细胞介素-6(IL-6)、肿瘤坏死因子-a(TNF-a)与超敏C反应蛋白(hs-CRP)指标水平变化。结果 与单纯应用甲硝唑治疗的对照组慢性宫颈炎患者相比,研究组显效和好转的人数更多,治疗有效率更高(P <0.05),在不良反应发生情况方面,应用保妇康栓联合甲硝唑的研究组出现不良反应的患者人数更少,不良反应发生率更低(P <0.05)。在治疗前后两组患者各项指标水平变化方面,治疗前,两组IL-6、TNF-a和hs-CRP水平对比无显著差异(P>0.05),治疗后,两组各项指标水平皆显著降低,且研究组下降幅度更加理想(P <0.05)。结论 在临床针对慢性宫颈炎患者构建的治疗活动中,可应用保妇康栓联合甲硝唑对患者进行治疗,该项治疗方案相比于单纯应用甲硝唑而言,效果更加理想,可优化临床疗效,减轻患者炎性反应,减少患者不良反应,最大程度的保障治疗安全。

Objective To evaluate the clinical efficacy of a treatment regimen of baomaternal kangthrombo combined with metronidazole in patients with chronic cervicitis. Methods A total of 80patients with chronic cervicitis treated in our hospital between July 2019 and July 2020 were selected as study subjects, based on the difference in medication content between patients with chronic cervicitis,divided into groups on average, 40 patients each, the control group was treated with metronidazole alone, and the study group was treated with metronidazole combined with maternal protective thrombosis to observe the treatment response rates of the two groups. Incidence of adverse effects and changes in serum levels of interleukin-6(IL-6), tumor necrosis factor-A(TNF-a), and Hypersensitivity C-Reactive Protein(hs CRP) indicators in different stages. Results Compared with the control group of patients with chronic cervicitis treated with metronidazole alone, the study group had a higher number of patients who showed good effects and a higher treatment efficacy rate, P <0.05, in terms of the occurrence of adverse effects, the study group that applied BMT combined with metronidazole had a lower number of patients who experienced adverse effects and a lower incidence of adverse effects,P < 0.05. In terms of the changes in the levels of each indicator in the two groups of patients before and after treatment, there was no significant difference in the levels of IL-6, TNF-a and hs CRP between the two groups before treatment, P >0.05, and after treatment, the levels of each indicator in the two groups were significantly reduced, and the decrease in the study group was more desirable, P <0.05. Conclusion In the clinical activity constructed for patients with chronic cervicitis, patients can be treated with BMT combined with metronidazole, and this treatment regimen is more desirable than metronidazole alone,which can optimize the clinical efficacy, alleviate inflammatory reactions in patients, reduce adverse reactions in patients, and maximize the safety of safe treatment.