高血压合并心力衰竭采用贝那普利及美托洛尔的疗效评价

Effect Evaluation of Benazepril and Metoprolol For Hypertension Complicated With Heart Failure

目的评价高血压合并心力衰竭采用贝那普利及美托洛尔的疗效。方法纳入本次研究的对象均从我院近期(2019年7月-2020年6月)收治的高血压合并心力衰竭患者中选取。通过纳入和排除标准筛选出118例患者作为研究对象。随机平均分两组,一组名为对照组,一组名为观察组。对照组给予贝那普利治疗;观察组给予贝那普利+美托洛尔治疗,对比两组治疗后的效果。结果统计分析两组治疗前后组内及治疗后组间SBP、DBP、NYHA、GMP-140、CT-1、BNP、AngⅡ、ADM、ADT的结果为P<0.05。结论高血压合并心力衰竭采用贝那普利及美托洛尔治疗在降低血压和心功能分级、抑制血小板活化和血管收缩、减轻心肌损伤方面的疗效明显。

Objective To evaluate effect of benazepril and metoprolol in treatment of hypertension complicated with heart failure.Methods The paper chose 118 patients with hypertension complicated with heart failure recently treated in our hospital(from July 2019 to June 2020)as study subjects,without loss of follow-up during the study,and divided them into control group and observation group with inclusion and exclusion criteria randomly.Control group was treated with benazepril,and observation group with benazepril+metoprolol.Results Statistical analysis of SBP,DBP,NYHA,GMP-140,CT-1,BNP,Ang II,ADM and ADT between two groups before and after treatment showed P<0.05.Conclusion Benazepril and metoprolol can achieve significant effect in reducing blood pressure and cardiac function grade,inhibit platelet activation and vasoconstriction,and reduce myocardial injury of patients.