安列克与宫颈双球囊在宫缩乏力性产后出血治疗中的疗效观察

Curative Effect of Anlieke and Cervical Double Balloon in the Treatment of Postpartum Hemorrhage Due to Uterine Asthenia

目的观察安列克与宫颈双球囊在宫缩乏力性产后出血患者治疗中的临床疗效。方法选取本院2019年1月-2020年6月住院的宫缩乏力性产后出血80例患者为对象,随机数字表法分为安列克组(给予患者安列克治疗)、球囊组(给予患者宫颈双球囊处理),每组40例。比较两组临床效果,治疗前后观察两组血细胞指标[红细胞(RBC)、血红蛋(Hb)和红细胞比容/压积(HCT)水平、凝血酶原时间(PT)、部分凝血活酶时间(APTT)、纤维蛋白(FIB),比较两组并发症发生率。结果处理后1h安列克组阴道出血量、输血量较球囊组明显高,而处理后2h、24h两组阴道出血量、红细胞下降值、输血量较处理后1h的明显降低,且处理后24h安列克组较球囊组明显低(P<0.05)。与同组治疗前比较,治疗后仅球囊组RBC、Hb、HCT明显降低,且治疗后安列克组RBC、Hb、HCT明显高于球囊组(P<0.05),与同组治疗前比较,治疗后两组PT、APTT明显降低,安列克组明显低于球囊组(P<0.05),FIB明显升高,安列克组明显高于球囊组(P<0.05)。两组并发症发生率比较差异无统计学意义(P>0.05),安列克组产褥病发生率明显低于球囊组(P<0.05)。结论安列克与宫颈双球囊在宫缩乏力性产后出血患者均有明显的止血效果,其中宫颈双球囊紧急止血效果更为明显,而安列克治疗宫缩乏力性产后出血则利于患者有效止血、贫血情况的改善、子宫收缩功能的提高和产褥病的减少,在临床应用中值得推广。

Objective The purpose of this study was to observe the clinical effects of Anlieke and cervical double balloon in the treatment of patients with postpartum hemorrhage due to uterine asthenia.Methods This study included 80 patients with postpartum hemorrhage due to uterine asthenia who were hospitalized in the hospital between January 2019 and June 2020.The patients enrolled were divided into Anlieke group(patients treated with Anlieke)and balloon group(patients treated with cervical double balloon)by random number table method,with 40 patients in each group.The clinical effects of the two groups were compared,and red blood cell(RBC),hemoglobin(Hb),hematocrit(HCT),prothrombin time(PT),activated partial thromboplastin time(APTT)and fibrinogen(FIB)in the two groups were observed before and after treatment.The incidence of complications was compared between the two groups.Results The vaginal bleeding volume and blood transfusion volume of the Anlieke group at 1h after treatment were significantly larger than those of the balloon group.The vaginal bleeding volume,decreased value of red blood cells and blood transfusion volume of the two groups at 2h and 24h after treatment were significantly lower than those at 1h after treatment.Besides,the above indicators in the Anlieke group at 24h after treatment were significantly lower than those in the balloon group(P<0.05).Compared with the same group before treatment,RBC,Hb and HCT in the balloon group were significantly reduced after treatment,and were significantly lower than those in the Anlieke group(P<0.05).After treatment,PT,APTT were significantly reduced in the two groups,and these indicators in the Anlieke group were significantly lower than those in the balloon group(P<0.05).FIB was significant increased,and FIB in the Anlieke group was significantly higher than that in the balloon group(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05),but the incidence of puerperal disease in Anlieke group was significantly lower than that in balloon group(P<0.05).Conclusion Both Anlieke and cervical double balloon can achieve significant hemostatic effects in patients with postpartum hemorrhage due to uterine asthenia.The emergency hemostatic effect of cervical double balloon is more obvious,while Anlieke is more conducive to effective hemostasis,improvement of anemia and uterine contraction function as well as reduction of puerperal disease.