腹腔镜结肠癌全系膜切除术治疗结肠癌患者的效果

Effects of laparoscopic total mesenteric resection on patients with colon cancer

目的:观察腹腔镜结肠癌全系膜切除术治疗结肠癌患者的效果。方法:选取80例结肠癌患者为研究对象,按随机数字表法将其分为对照组与观察组各40例。对照组采用传统开腹结肠癌全系膜切除术治疗,观察组采用腹腔镜结肠癌全系膜切除术治疗,比较两组手术相关指标水平、治疗总有效率、并发症发生率、远处转移率、局部复发率和无瘤生存率。结果:两组手术时间比较,差异无统计学意义(P>0.05);观察组术中出血量少于对照组,首次排气时间短于对照组,淋巴结清扫数目多于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率为92.50%(37/40),高于对照组的72.50%(29/40),差异有统计学意义(P<0.05);观察组并发症发生率为5.00%(2/40),低于对照组的22.50%(9/40),差异有统计学意义(P<0.05);两组远处转移率比较,差异无统计学意义(P>0.05);观察组局部复发率低于对照组,无瘤生存率高于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜结肠癌全系膜切除术治疗结肠癌患者可改善手术相关指标水平,提高治疗总有效率和无瘤生存率,以及降低并发症发生率和局部复发率,其效果优于传统开腹结肠癌全系膜切除术治疗。

Objective:To observe effects of laparoscopic total mesenteric resection on patients with colon cancer.Methods:80 patients with colon cancer were selected as the research objects,and were divided into control group and observation group according to the random number table method,40 cases in each group.The control group was treated with traditional open radical resection for colon cancer,while the observation group was treated with laparoscopic total mesenteric resection.The levels of surgery-related indicators,the total effective rate of treatment,the incidence of complications,the distant metastasis rate,the local recurrence rate and the tumor-free survival rate were compared between the two groups.Results:There was no significant difference in the operation time between the two groups(P>0.05).The intraoperative blood loss in the observation group was less than that in the control group;the first exhaust time was shorter than that in the control group;the number of lymph nodes dissected was higher than that in the control group;and the differences were statistically significant(P<0.05).The total effective rate of the observation group was 92.50%(37/40),which was higher than 72.50%(29/40)of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was 5.00%(2/40),which was lower than 22.50%(9/40)in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the distant metastasis rate between the two groups(P>0.05).Further,the local recurrence rate in the observation group was lower than that in the control group;the tumor-free survival rate was higher than that in the control group;and the differences were statistically significant(P<0.05).Conclusions:Laparoscopic total mesenteric resection of colon cancer in the treatment of the colon cancer patients can improve the levels of surgery-related indicators,improve the total effective rate and the tumor-free survival rate,and reduce the incidence of complications and the local recurrence rate Moreover,it is superior to traditional open surgery radical resection for colon cancer.