调节性B细胞的作用机制及其在相关疾病中的研究进展

Progress in the mechanism of regulatory B cells and its role in human diseases

调节性B细胞(regulatory B cells,Bregs)是一群具有免疫调节功能的细胞,通过抑制过度炎症反应从而调节疾病进展,是一种在免疫功能紊乱等状态下发挥重要作用的保护性细胞。本文就其来源、功能、作用机制及其在自身免疫性疾病、感染及肿瘤方面的相关研究进展作一综述。

Regulatory B cells(Bregs)are a group of cells with immunoregulatory function.They can regulate the progression of diseases by inhibiting excessive inflammatory responses and serve as critical protective cells in immune disorders and other conditions.This article reviewed the source,function and mechanism of Bregs and its role in autoimmune diseases,infection and tumor.