肺部炎性肌纤维母细胞瘤的诊疗:单中心回顾性研究并文献综述

The diagnosis and treatment of pulmonary inflammatory myofibroblastic tumor:a single center retrospective study and literature review

肺部炎性肌纤维母细胞瘤是一种罕见的肺部肿瘤,临床医师缺乏对该疾病的充分认识。本文以本中心肺部炎性肌纤维母细胞瘤患者的病例资料为基础,对该疾病的既往报道做了全面的检索和简要的汇总分析。肺部炎性肌纤维母细胞瘤更容易出现在男性患者和右肺,其临床和影像学表现具有异质性。手术是最为重要的治疗方式,完整切除对患者的预后有很大意义,以克唑替尼为代表的靶向治疗可能对ALK突变阳性的患者有帮助。

Pulmonary inflammatory myofibroblastic tumor(PIMT)is a rare lung tumor that is poorly understood by clinicians.Based on the data of patients with PIMT in our center,a comprehensive search and a brief summary analysis of previous reports of the disease were carried out in this article.PIMTs were more likely to be present in male patients and in the right lung,and their clinical and radiographic findings were heterogeneous.Surgery is the most important treatment method,and complete resection is of great significance to the prognosis of patients.Targeted therapy represented by crizotinib may be helpful for patients with positive ALK mutations.