摘要
Recently,Wang et al.published a study in Nature that examined whether sera from individuals who received two or three doses of the inactivated vaccine could neutralize Omicron.1 Broad-spectrum and potent neutralizing antibodies were isolated from three-dose recipients,which could effectively neutralize strain pseudoviruses and authentic viruses of SARS-CoV-2 of concern(VOCs),including Omicron.In addition,the cryo-EM structures of the Omicron spike were elucidated,revealing a new critical immune evasion site and mechanism for the Omicron strain.
