静脉瓣功能障碍致假性Kaposi肉瘤1例报告并文献回顾

Pseudo-Kaposi sarcoma caused by venous valve dysfunction:a case report and literature review

背景与目的:假性Kaposi肉瘤,又称肢端血管性皮炎,是一种罕见的血管外科疾病。本文通过报告1例静脉瓣功能障碍致假性Kaposi肉瘤病例,结合文献回顾探讨其临床病理特征及诊治。方法:回顾性分析1例假性Kaposi肉瘤患者的临床病例资料,结合国内外文献总结假性Kaposi肉瘤的病因、分型、临床表现、病理、诊断及治疗。结果:患者男性,37岁。长期从事站立性体力劳动,两踝关节内侧下方数个暗紫红色瘀斑,近1个月久站后皮损处疼痛。结合病史、病理切片及辅助检查,诊断为“假性Kaposi肉瘤”。经穿弹力袜、促进静脉回流、抗凝、改善循环后,双下肢皮损处无明显疼痛,皮损较前无明显扩大或增多。结论:静脉瓣功能障碍与假性Kaposi肉瘤发生发展相关,较为罕见且鉴别诊断存在一定困难,需结合皮损特点、病理及血管影像特点综合考虑,目前无特异性治疗。

Background and Aims:Pseudo-Kaposi sarcoma,also known as acroangiodermatitis,is a rare disease in the field of vascular surgery.Hence,this article was conducted to investigate the clinicopathologic characteristics as well as the diagnosis and treatment of this disease through reporting a case of pseudo-Kaposi sarcoma caused by venous valve dysfunction,combined with literature review.Methods:The clinical data of one patient with pseudo-Kaposi sarcoma were retrospectively analyzed,and the etiology,typology,clinical manifestations,pathological features,diagnosis,and treatment of pseudo-Kaposi sarcoma were summarized with domestic and foreign literature review.Results:The patient was a 37-year-old man who had been engaged in physical work in a standing position for a long time.He had several dark purplish-red ecchymoses on the interior sides of the lower portions of both ankles and had pain after prolonged standing during the past month.He was diagnosed with"pseudo-Kaposi sarcoma"by combining clinical and pathological examinations and adjuvant examinations.After wearing elastic stockings,promoting venous reflux,anticoagulation,and improving circulation,there was no obvious pain in the skin lesion on both lower limbs,and no development or growth of the skin lesions were noted.Conclusion:Venous valve dysfunction is associated with the occurrence and development of pseudo-Kaposi sarcoma,which is rare and difficult to make a differential diagnosis,and needs to be considered comprehensively according to the lesion characteristics,pathology,and angiographic features.There is currently no specific and effective treatment.