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米非司酮治疗女性子宫肌瘤的研究进展 被引量:1

Research progress of mifepristone in the treatment of female hysteromyoma
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摘要 子宫肌瘤是由子宫平滑肌组织增生形成的良性肿瘤,其病因并未明确,但多数研究结果显示与遗传、激素、干细胞等因素有关。流行病学调查结果显示,育龄妇女子宫肌瘤的发病率明显提升,30~50岁的妇女是主要发病人群,因肌瘤多无或很少有症状,临床报道发病率远低于肌瘤真实发病率。根据生长位置的不同,可划分为浆膜下肌瘤、肌壁间肌瘤、黏膜下肌瘤或宫颈肌瘤、阔韧带肌瘤等,不同类型的子宫肌瘤患者可能会造成月经过多、贫血,下腹部包块或排尿、排便困难等临床表现。上述问题的出现都会对患者的身心健康产生严重影响,因此也就需要及时给予治疗。在临床上对该病症的药物治疗中,米非司酮的应用率相对较高,受到临床相关研究人员认可,能够有效改善患者的临床症状。基于此,本文以综述的角度讨论米非司酮治疗女性子宫肌瘤的研究进展。 Hysteromyoma is a benign tumor formed by the proliferation of uterine smooth muscle tissue.Its etiology is not clear in clinic,but most research results show that it is related to heredity,hormones,stem cells and so on.According to the results of clinical investigation,the incidence rate of hysteromyoma in women has increased significantly in recent years.Women aged 30-50 are the main population suffered from the disease.Because most of the leiomyomas have no or few symptoms,the clinically reported incidence rate is far lower than the true incidence rate of leiomyomas.According to the different growth location,it can be divided into subserosal leiomyoma,intramural leiomyoma,submucosal leiomyoma or cervical leiomyoma,broad ligament leiomyoma,etc.Patients with different types of hysteromyoma may cause clinical manifestations such as excessive menstruation,anemia,lower abdominal mass or difficulty in urination and defecation.The occurrence of the above problems will have a serious impact on the physical and mental health of patients,so it needs to be treated in time.In the clinical drug treatment of this disease,the application rate of mifepristone is relatively high,which is recognized by clinical researchers and can effectively improve the clinical symptoms of patients.Based on this,this paper discusses the research progress of mifepristone in the treatment of female hysteromyoma from the perspective of review.
作者 苏艳艳 SU Yan-yan(Department of Gynecology,People's Hospital of Wuqing District,Tianjin 301700,China)
出处 《中国城乡企业卫生》 2022年第6期38-40,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 子宫肌瘤 米非司酮 治疗 研究进展 Hysteromyoma Mifepristone Treatment Research progress
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