药物洗脱支架的现况与发展

State-of-the-art and outlook of drug-eluting stents

对于动脉粥样硬化导致的血管狭窄等腔内血管疾病而言,药物洗脱支架植入是一种行之有效的治疗方法。与传统支架相比,药物洗脱支架提供的抗增殖药物可以显著降低血管的再狭窄,允许在更晚期和更复杂的血管疾病中使用支架介入治疗。本文将综述目前不同药物洗脱支架的载药类型、现况及其研究进展,以期帮助临床医生和科研人员们充分了解药物洗脱支架,从而在实际应用中做出更合理化的选择,并对载药支架的未来发展与前景进行展望。

Implantation of drug-eluting stents(DES)is one of the most effective treatment for intraluminal vascular diseases such as vascular stenosis caused by atherosclerosis.Antiproliferative drugs offered by could significantly reduce the restenosis of blood vessels,which is beneficial to interventional therapy in more advanced and complex vascular diseases.This review sumarizes the state-of-the-art of the DES based on the function of loaded drug and material of the stents.We hope this review can provide basic information of DES for clinicians and researchers to make more rational choices in practical applications.Moreover,this review also propses the prospects of drug-loaded stents.