经肌张力修正的正常成人骨导前庭诱发肌源性电位特征

Myotonia-rectified bone-conducted vibration vestibular evoked myogenic potential in normal adults

目的:观察并分析正常成人骨导前庭诱发肌源性电位(BCV-VEMP)相关参数特征,比较肌张力修正前后双侧幅值、幅值不对称比的变化,为耳石器及其传导通路的功能评估以及眩晕疾病的诊断提供更加精准的参考依据。方法:选取30名(60耳)20~32岁正常成年人,以坐姿进行骨导颈肌VEMP(BCV-cVEMP)和眼肌VEMP(BCV-oVEMP)测试。使用B-81骨导耳机给声,刺激强度为129.5 FL,记录修正前后的BCV-cVEMP和BCV-oVEMP的P1、N1潜伏期、P1-N1波间期、P1-N1幅值、幅值不对称比等。结果:BCV-cVEMP和BCV-oVEMP在正常成人中的引出率均为100%。BCV-cVEMP的P1、N1潜伏期分别为(16.00±2.02)ms、(25.04±2.57)ms,波间期为(9.04±1.78)ms。BCV-oVEMP的N1、P1潜伏期分别为(10.39±0.81)ms、(15.85±1.00)ms,波间期为(5.46±0.86)ms。BCV-cVEMP和BCV-oVEMP修正前后的幅值差异均有统计学意义(P<0.05)。修正后BCV-cVEMP幅值不对称比为(17.03±9.14)%,修正后BCV-oVEMP幅值不对称比为(20.43±11.65)%。结论:BCV-VEMP是一种可行且有效的耳石器功能检测手段。建立修正后的幅值、幅值不对称比等参数的正常范围可为前庭耳石器及其传导通路功能评估及诊断提供更准确的参考依据。

Objective:To study the characteristics of bone-conducted vibration vestibular evoked myogenic potential(BCV-VEMP)in normal adult with and without myotonia rectification,and to provide accurate reference for clinical vestibular function evaluation.Methods:Thirty normal adults(60 ears)aged 20-32 years old were selected to receive BCV-VEMP in a sitting position.BCV-VEMP were induced by B-81 bone-conducted vibrator at 129.5 FL,the P1 latency,N1 latency,P1-N1 interval,amplitude,and amplitude asymmetry ratios were recorded in two test conditions.Results:Clear and repeatable waveforms of BCV-cVEMP and BCV-oVEMP were obtained in all normal adults.The P1 and N1 latencies of BCV-cVEMP were(16.00±2.02)ms and(25.04±2.57)ms,respectively,P1-N1 interval was(9.04±1.78)ms.The N1 and P1 latencies of BCV-oVEMP were(10.39±0.81)ms and(15.85±1.00)ms,respectively,iand interval was(5.46±0.86)ms.The amplitudes of BCV-cVEMP and BCV-oVEMP in two test conditions were statistically significant(P<0.05).The amplitude asymmetry ratios of BCV-cVEMP and BCV-oVEMP after rectification were(17.03±9.14)%and(20.43±11.65)%,respectively.Conclusion:BCV-VEMP is a feasible and reliable tool for vestibular function assessment.The establishment of a normal values such as amplitude and amplitude asymmetry ratio after rectification can provide a more reliable and accurate reference.