高频超声联合低频超声检查诊断新生儿颅脑病变的临床价值研究

Clinical Value Study of High Frequency Ultrasound Combined with Low Frequency Ultrasound in the Diagnosis of Neonatal Craniocerebral Lesions

目的:探讨高频联合低频超声对新生儿颅脑病变的诊断价值,为新生儿颅脑病变的诊断提供依据。方法:选择2019年1月-2021年4月安徽省儿童医院接诊并疑似出现颅脑病变的新生儿62例作为研究对象,所有研究对象均应用高频超声联合低频超声探头对颅脑进行检查,并住院治疗。比较高频超声、低频超声、高频联合低频超声对新生儿颅脑病变的检出率;根据出院诊断结果比较高频超声、低频超声及联合检查与临床诊断符合情况及对颅脑病变的诊断价值。结果:高频超声检出颅脑病变35例(56.45%),低频超声检出颅脑病变27例(43.55%),高频超声联合低频超声检出颅脑病变53例(85.48%),高频超声联合低频超声对新生儿颅脑病变的检出率显著高于高频超声、低频超声(P<0.05);高频超声对新生儿颅脑病变的检出率显著高于低频超声(P<0.05)。高频联合低频超声对新生儿颅脑疾病诊断与临床诊断总体符合率高于高频超声、低频超声,高频超声对新生儿颅脑疾病诊断与临床诊断总体符合率高于低频超声(P<0.05)。高频联合低频超声对新生儿不同颅脑疾病诊断灵敏度、准确度显著高于高频超声、低频超声(P<0.05),高频超声对新生儿不同颅脑疾病诊断灵敏度、准确度显著高于低频超声(P<0.05),三种检查方法对新生儿不同颅脑疾病诊断特异度比较无统计学意义(P>0.05)。结论:高频联合低频超声检查诊断新生儿不同颅脑病变的灵敏度、准确度均较高,具有一定的临床应用价值。

Objective:To explore the diagnostic value of high frequency combined with low frequency ultrasound in neonatal craniocerebral lesions,so as to provide basis for the diagnosis of neonatal craniocerebral lesions.Methods:62 newborns with suspected craniocerebral lesions who were received in Anhui children’s Hospital from January 2019 to April 2021 were selected as the research objects,All subjects were examined with high frequency ultrasound combined with low frequency ultrasound probe and hospitalized.The detection rates of high frequency ultrasound,low frequency ultrasound and high frequency combined with low frequency ultrasound were compared.According to the discharge diagnosis results,the coincidence of high frequency ultrasound,low frequency ultrasound and combined examination with clinical diagnosis and the diagnostic value of craniocerebral lesions were compared.Results:Craniocerebral lesions were detected in 35 cases(56.45%)by high frequency ultrasound,craniocerebral lesions were detected in 27 cases(43.55%)by low frequency ultrasound,and craniocerebral lesions were detected in 53 cases(85.48%)by high frequency ultrasound combined with low frequency ultrasound,and the detection rate of neonatal craniocerebral lesions by high frequency ultrasound combined with low frequency ultrasound was significantly higher than that of high frequency ultrasound and low frequency ultrasound(P<0.05).The detection rate of neonatal craniocerebral lesions by high frequency ultrasound was significantly higher than that by low frequency ultrasound(P<0.05).The overall coincidence rate of diagnosis and clinical diagnosis of neonatal craniocerebral diseases by high frequency combined with low frequency ultrasound was higher than that by high frequency ultrasound and low frequency ultrasound,and the overall coincidence rate of diagnosis and clinical diagnosis by high frequency ultrasound was higher than that by low frequency ultrasound(P<0.05).The diagnostic sensitivity and accuracy of high frequency combined with low frequency ultrasound were significantly higher than those of high frequency ultrasound and low frequency ultrasound in different craniocerebral diseases of neonates(P<0.05).The diagnostic sensitivity and accuracy of high frequency ultrasound were significantly higher than those of low frequency ultrasound in different craniocerebral diseases of neonates(P<0.05).There was no statistical significance in the diagnostic specificity of the three examination methods for different craniocerebral diseases(P>0.05).Conclusion:High frequency combined with low frequency ultrasound has high sensitivity and accuracy in the diagnosis of different neonatal craniocerebral lesions,which has certain clinical application value.