摘要
幽门螺杆菌(Hp)是胃癌发生的主要危险因素,Hp慢性感染可介导正常黏膜向慢性萎缩性胃炎转变,进而发展为癌前病变,此过程被称为炎-癌转化。基于伏邪学说,中医学认为炎-癌进展与湿热关系密切,瘀血、痰浊、热毒是恶化发展的重要病理因素。
Helicobacter pylori(Hp)infection is the major risk factor linked to gastric cancer.The transition from normal mucosa to chronic atrophic gastritis triggered primarily by Hp infection,initiates precancerous lesions which may then progress to intestinal metaplasia and dysplasia,which is called inflammation-related gastric carcinogenesis.Based on the theory of insidious disease,the pathogenesis of gastric cancer is mainly related to damp heat,with blood-stagnation,phlegm coagulation and heattoxicity exacerbating tumorgenesis and development during gastric precancerous lesions.
作者
张泰
张北华
马祥雪
王凤云
尹晓岚
陈婷
唐旭东
ZHANG Tai;ZHANG Bei-hua;MA Xiang-xue;WANG Feng-yun;YIN Xiao-lan;CHEN Ting;TANG Xu-dong(Department of Gastroenterology,Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China;China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2022年第6期3132-3136,共5页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
中医药行业科研专项(No.201407001-12)。
关键词
炎-癌转化
幽门螺杆菌
胃癌
伏邪学说
慢性萎缩性胃炎
湿热
Inflammation-related carcinogenesis
Helicobacter pylori(Hp)
Gastric cancer
Theory of insidious disease
Chronic atrophic gastritis(CAG)
Damp heat
