咽喉反流性疾病诊治的研究进展

Progress in diagnosis and treatment of laryngopharyngeal reflux disease

咽喉反流性疾病(LPRD)是指胃内容物(胃酸、胃蛋白酶、胆汁酸等)以液体或气体的形式,直接或间接反流至食管上括约肌以上部位,引起咽部、喉部一系列症状与体征的总称。近年来LPRD患病率逐年增高,受到了许多临床学者的关注和重视。LPRD发病机制复杂多样,国内外尚缺乏统一的诊治标准,在临床诊疗过程中存在着诊治不规范的情况。基于此,本文就咽喉反流性疾病的诊断及治疗的研究进展进行综述,以期为临床诊治LPRD提供参考。

Laryngopharyngeal reflux disease is a reflux of gastric contents(gastric acid,pepsin,bile acid,etc.)directly or indirectly into the upper esophageal sphincter in the form of liquid or gas,causing a series of symptoms and signs in the pharynx and larynx.In recent years,LPRD has attracted the attention of many clinical scholars,and its prevalence is increasing year by year.LPRD has no specific clinical manifestations,and its pathogenesis is complex and diverse.There is still a lack of unified diagnosis and treatment standards at home and abroad,and the diagnosis and treatment are not standardized in the process of clinical diagnosis and treatment.This article reviews the diagnosis and treatment of these diseases.