中西医结合治疗慢性阻塞性肺疾病合并肺心病患者的效果观察

Effects of integrated traditional chinese and Western medicine treatment in patients with chronic obstructive pulmonary disease and pulmonary heart disease

目的:探讨中西医结合治疗慢性阻塞性肺疾病(以下简称慢阻肺)合并肺心病患者的效果。方法:选取我院2019年1月—2020年12月收治的86例慢阻肺合并肺心病患者,将其按照随机的原则进行分组。对照组43例患者使用常规西药治疗,观察组43例患者使用中西医结合治疗,将两组患者治疗后的总有效率、临床相关指标及治疗前后肺功能、血气分析指标、临床症状与体征积分进行比较。结果:观察组治疗后的总有效率为93.02%,高于对照组治疗后的76.74%,差异有统计学意义(P<0.05)。治疗前,两组患者的血清B型脑钠肽、肺动脉收缩压及右心室射血分数指标相比,差异均无统计学意义(P>0.05);治疗后,观察组患者血清B型钠尿肽与肺动脉收缩压优于对照组,左室射血分数高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者肺功能指标比较,差异无统计学意义(P>0.05);治疗后,观察组FEV_(1)、FEV_(1)/FVC高于对照组,FRC低于对照组,组间差异有统计学意义(P<0.05)。两组治疗前后pH值比较,差异均无统计学意义(P>0.05)。治疗前,两组PaO_(2)、PaCO_(2)比较,差异无统计学意义(P>0.05);治疗后,观察组PaO_(2)高于对照组,PaCO_(2)低于对照组,差异有统计学意义(P<0.05)。两组治疗前临床症状与体征评分比较,差异无统计学意义(P>0.05);治疗后,观察组临床症状与体征评分低于对照组,差异有统计学意义(P<0.05)。结论:中西医结合治疗慢阻肺并肺心病患者,可有效改善患者的临床症状、肺功能及血清学指标,促进患者生活质量及身心健康的恢复,具有确切的治疗效果。

Objective To explore the treatment effect of integrated traditional Chinese and Western medicine in patients with chronic obstructive pulmonary disease complicated with pulmonary heart disease.Methods A total of 86 patients with chronic obstructive pulmonary disease and pulmonary heart disease admitted to our hospital from January 2019 to December 2020 were selected as the research objects,and they were divided into groups according to the principle of randomization.43 patients in the control group were treated with drugs,and 43 patients in the observation group were treated with integrated traditional Chinese and Western medicine.The total effective rate,clinical related indexes,pulmonary function,blood gas analysis indexes,clinical symptoms and signs scores before and after treatment were compared between the two groups.Results The total effective rate of the observation group after treatment was 93.02%,which was higher than 76.74%of the control group after treatment,and the difference between the two groups was statistically significant(P<0.05).Before treatment,there was no significant difference in the clinical indicators between the two groups(P>0.05);After treatment,the serum B-type natriuretic peptide and pulmonary artery systolic blood pressure in the observation group were lower than those in the control group,and the left ventricular ejection fraction was higher than that in the control group,and the difference between the two groups was statistically significant(P<0.05).Before treatment,there was no significant difference in pulmonary function indexes between the two groups(P>0.05);After treatment,the FEV_(1) and FEV_(1)/FVC in the observation group were higher than those in the control group,and FRC was lower than that in the control group,and the difference between the two groups was statistically significant(P<0.05).There was no significant difference in pH value between the two groups before and after treatment(P>0.05).Before treatment,the PaO_(2) and PaCO_(2) in the two groups were similar,and the difference was not statistically significant(P>0.05).There was no significant difference in the scores of clinical symptoms and signs between the two groups before treatment(P>0.05);After treatment,the scores of clinical symptoms and signs in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Integrative traditional Chinese and Western medicine in the treatment of patients with COPD and pulmonary heart disease can effectively improve the clinical symptoms,pulmonary function and serological indexes of patients,and promote the recovery of patients’quality of life and physical and mental health,with definite therapeutic effects.