80例突发性耳聋伴眩晕症状患者临床特征、MRI影像学特点及临床转归分析

Analysis of Clinical Features,MRI Characteristics and Clinical Outcomes of 80 Patients with Sudden Deafness Complicated with Vertigo

目的分析突发性耳聋伴眩晕症状患者的临床特征、MRI影像学特点及临床转归情况。方法回顾性分析2017年6月至2019年6月本院收治的80例突发性耳聋伴眩晕患者(伴眩晕组)和同期治疗的75例突发性耳聋不伴眩晕患者(不伴眩晕组)的临床资料,分析突发性耳聋伴眩晕患者的MRI影像学特点及影响患者临床转归的相关因素。结果两组患者的基础疾病、听力损失程度及临床疗效比较,存在统计学差异(均P<0.05)。伴眩晕组的85只患耳中,23只患耳(27.06%)存在膜迷路积水,图像显示前庭信号减弱;62只患耳(72.94%)未见明显积水征象。临床转归分析结果显示,眩晕持续时间越长、听力损失程度越重、听力曲线分型为全聋型,患者治疗有效率越低(P<0.05)。结论突发性耳聋伴眩晕患者多合并基础疾病,听力损失程度较高;MRI图像特征为前庭信号减弱,可见膜迷路积水;患者的临床转归与眩晕持续时间、听力损失程度和听力曲线分型有关。

Objective To analyze the clinical features,MRI characteristics and clinical outcomes of patients with sudden deafness complicated with vertigo.Methods The clinical data of 80 patients with sudden deafness complicated with vertigo(vertigo group),and 75 patients with sudden deafness but without vertigo(non-vertigo group)who were treated in the hospital between June 2017 and June 2019 were retrospectively analyzed.MRI characteristics of the vertigo group,and related factors affecting clinical outcomes were analyzed.Results There were statistically significant differences between the two groups in underlying diseases,the degree of hearing loss and clinical efficacy(P<0.05).Among the 85 affected ears of vertigo group,there were 23(27.06%)ears with endolymphatic hydrops,and the image showed weakened vestibular signals.No obvious sign of hydrops was observed in 62(72.94%)affected ears.Clinical outcome analysis results showed that the longer the duration of vertigo,the more severe the degree of hearing loss,and the hearing curve was total deafness type,the lower the effective rate of treatment.(P<0.05).Conclusion Patients with sudden deafness complicated with vertigo often have underlying diseases and more severe hearing loss.MRI image features include weakened vestibular signals and endolymphatic hydrops.The clinical outcome is related to the duration of vertigo,degree of hearing loss and type of hearing curve.