MRI联合血清肿瘤标志物对BOT及Ⅰ期EOC的鉴别诊断价值

Differential Diagnosis Value of MRI Combined with Serum Tumor Markers for BOT and Stage Ⅰ EOC

目的研究MRI联合血清肿瘤标志物对BOT及Ⅰ期EOC的鉴别诊断价值。方法回顾性分析本院2017年6月至2019年9月收治的经手术病理证实的58例BOT患者和49例EOC患者的临床资料。比较两组患者MRI特征及血清肿瘤标志物含量,分析MRI检查联合血清肿瘤标志物检测鉴别诊断疾病的准确率。结果BOT组与EOC组患者肿瘤发生部位、肿瘤大小、分隔数比较差异均无统计学意义(P>0.05)。BOT组实性部分大小、分隔厚度均小于EOC组(P<0.05)。BOT组患者的血清CA125含量低于EOC组,但两组比较差异无统计学意义(P>0.05);EOC组患者的血清HE4含量显著高于BOT组,两组比较差异具有统计学意义(P<0.05);MRI检查联合血清肿瘤标志物检测BOT和EOC的诊断准确率为93.46%(100/107),明显高于单一的血清肿瘤标志物检测、MRI检查(P<0.05)。结论MRI检查可清楚显示Ⅰ期EOC和BOT的影像学特点,结合血清肿瘤标志物可有效鉴别Ⅰ期EOC和BOT,提高诊断准确率。

Objective To investigate the differential diagnosis value of MRI combined with serum tumor markers for BOT and stage I EOC.Methods The clinical data of 58 patients with BOT and 49 patients with EOC confirmed by surgery and pathology treated in our hospital from June 2017 to September 2019 were retrospectively analyzed.The MRI signs and levels of serum tumor markers were compared between the two groups,and the accuracy of differential diagnosis between MRI and serum tumor markers was analyzed.Results There were no significant differences in tumor location,tumor size and number of division between BOT group and EOC group(P>0.05).The size of the solid part and separation thickness in the BOT group were smaller than those in the EOC group(P<0.05).The serum CA125 level in the BOT group was lower than that in the EOC group,but there was no significant difference between the two groups(P>0.05).The serum HE4 level of the patients in the EOC group was significantly higher than that in the BOT group,difference was statistically significant(P<0.05);the diagnostic accuracy of MRI combined with serum tumor markers for BOT and EOC was 93.46%(100/107),which was significantly higher than that of single serum tumor markers and MRI(P<0.05).Conclusion MRI examination can clearly show the imaging features of stage I EOC and BOT.Combined with serum tumor markers,it can effectively identify stage I EOC from BOT,and improve the diagnostic accuracy.