眼针配合热敏灸治疗肝气郁结型中风后抑郁疗效观察

Observation of the Curative Efficacy of Eye Acupuncture Combined with Heat Sensitive Moxibustion on Post-Stroke Depression of Liver Qi Stagnation Type

目的:观察眼针配合热敏灸治疗肝气郁结型中风后抑郁的临床疗效。方法:选取2020年1月至2022年1月洛阳市中医院诊治的肝气郁结型中风后抑郁患者62例,采用简单随机分组法分为观察组与对照组,每组31例。所有患者均给予基础治疗,控制好基础血糖、血压,积极预防并发症,并进行中风后康复训练,期间予以人文关怀和心理疏导。对照组另给予盐酸舍曲林片口服,观察组另给予眼针和热敏灸治疗。采用改良爱丁堡-斯堪的那维亚评分量表(modified edin-burgh scandinavian rating scale,MESS)及汉密尔顿抑郁量表(hamilton depression scale,HAMD)24项分别评估两组患者治疗前后神经功能和抑郁症状改善情况,检测两组患者治疗前后血清去甲肾上腺素、5-羟色胺、白细胞介素(interleukin,IL)-1β、同型半胱氨酸(homocysteine,Hcy)、超氧化物歧化酶(superoxide dismutase,SOD)水平。结果:两组治疗后MESS评分和HAMD24评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组治疗后精神抑郁、胸肋胀痛、嗳气频作症状评分低于治疗前,且观察组各项评分低于对照组,差异有统计学意义(P<0.05);观察组治疗后IL-1β、Hcy、SOD低于对照组,去甲肾上腺素、5-羟色胺水平高于对照组,差异有统计学意义(P<0.05);观察组有效率为97.30%,对照组有效率为81.08%,观察组有效率高于对照组,差异有统计学意义(P<0.05)。结论:眼针配合热敏灸可有效改善肝气郁结型中风后抑郁患者神经功能和抑郁症状,降低IL-1β、Hcy、SOD水平,升高去甲肾上腺素、5-羟色胺水平。

Objective: To observe the clinical efficacy of eye acupuncture combined with heat sensitive moxibustion on post-stroke depression of liver qi stagnation type.Methods: A total of 62 patients with post-stroke depression of liver qi stagnation type diagnosed and treated in Luoyang Hospital of Traditional Chinese Medicine from January 2020 to January 2022 were randomly divided into the observation group and the control group, with 31 cases in each group.All patients were given basic treatment, basic blood glucose and blood pressure were well controlled, complications were actively prevented, and post-stroke rehabilitation training was carried out, during which humanistic care and psychological counseling were given.The control group was additionally given Sertraline Hydrochloride Tablets orally, and the observation group was given eye acupuncture and heat sensitive moxibustion.Modified Edinburgh Scandinavian Rating Scale(MESS) and Hamilton Depression Scale(HAMD) 24 items were used to evaluate the improvement of neurological function and depressive symptoms of the two groups of patients before and after treatment, and the serum norepinephrine, 5-hydroxytryptamine, interleukin(IL)-1β,homocysteine(Hcy) and superoxide dismutase(SOD) levels before and after treatment were measured.Results: After treatment, the MESS score and HAMD24 score of the two groups were lower than those of the same group before treatment, and the above two scores of the observation group were lower than those of the control group, and all the differences were statistically significant(P<0.05).The symptom scores of depression, chest pain and belching frequency in the two groups after treatment were lower than those of the same group before treatment, and the scores of the observation group were lower than those in the control group, and all the differences were statistically significant(P<0.05).After treatment, IL-1β,Hcy and SOD in the observation group were lower than those in the control group, while the levels of norepinephrine and 5-hydroxytryptamine were higher than those in the control group, and all the differences were statistically significant(P<0.05).The effective rate of the observation group was 97.30%,which was higher than that of the control group: 81.08%,and the difference was statistically significant(P<0.05).Conclusion: Eye acupuncture combined with heat sensitive moxibustion can effectively improve the neurological function and depressive symptoms of post-stroke depression patients with liver qi stagnation, reduce IL-1β,Hcy, and SOD levels, and increase norepinephrine and serotonin levels.