个性化钛网联合屏障膜在引导骨再生修复牙槽骨缺损中的应用效果

Application of Personalized Peptide Net Combined with Barrier Membrane in Guided Bone Regeneration for Alveolar Bone Defect Repair

【目的】探讨个性化钛网联合屏障膜在引导骨再生(GBR)修复牙槽骨缺损中的应用效果。【方法】选取2019年1月至2020年10月在本院诊治的106例上前牙缺失牙槽骨缺损患者,按照随机数字表法分为观察组和对照组,每组53例。两组患者均采用GBR技术修复牙槽骨缺损,对照组使用常规屏障膜,观察组在对照组的基础上给予个性化钛网。比较两组骨增量、牙龈美学、牙周指标情况及术后并发症发生情况。【结果】术后6个月,观察组牙槽骨宽度大于对照组(P<0.05),牙槽骨宽度变化值低于对照组(P<0.05),种植修复的红色美学指数(PES)总分高于对照组(P<0.05);两组白色美学指数(WES)总分比较,差异无统计学意义(P>0.05)。两组术后6个月的探诊深度(PD)、附着水平(AL)均低于术前(P<0.05),两组术前、术后6个月的PD、AL比较,差异均无统计学意义(P>0.05)。两组术后1个月总并发症发生率比较,差异无统计学意义(P>0.05)。【结论】在GBR修复牙槽骨缺损中使用个性化钛网和屏障膜可增加缺损牙槽骨骨量及红色美学效果,提供稳定种植体环境,且安全性良好。

【Objective】To investigate the effect of personalized peptide mesh combined with barrier membrane in guided bone regeneration(GBR)for alveolar bone defect repair.【Methods】A total of 106 patients with alveolar bone defects with missing upper anterior teeth who were diagnosed and treated in our hospital from January 2019 to October 2020 were randomly divided into observation group and control group,with 53 cases in each group.GBR technique was used to repair alveolar bone defects in both groups,conventional barrier membrane was used in the control group,and personalized peptide net was given in the observation group on the basis of the control group.The bone increment,gingival aesthetics,periodontal index and postoperative complications were compared between the two groups.【Results】Six months after operation,the width of alveolar bone in the observation group was greater than that in the control group(P<0.05),the change of alveolar bone width was lower than that in the control group(P<0.05),and the total score of red aesthetic index(PES)of implant repair was higher than that in the control group(P<0.05);There was no significant difference in the total score of white aesthetic index(WES)between the two groups(P>0.05).The depth of detection(PD)and the level of adhesion(AL)of the two groups at 6 months after operation were lower than those before operation(P<0.05).There was no significant difference in PD and Al between the two groups at 6 months after operation(P>0.05).There was no significant difference between the two groups in the incidence of total complications one month after operation(P>0.05).【Conclusion】The use of personalized peptide net and barrier membrane in GBR repair of alveolar bone defects can increase the bone mass and red aesthetic effect of alveolar bone defects,provide a stable implant environment,and have good safety.