抗γ氨基丁酸B受体脑炎研究进展

A Review on Anti Gamma-aminobutyric Acid-B Receptor Encephalitis

自身免疫性脑炎(AE)是指免疫系统产生针对神经元抗原的自身抗体而引起的一类脑炎,抗γ氨基丁酸B受体(GABABR)脑炎是一种罕见的与抗神经元细胞表面抗体相关的AE。近年有关抗GABABR脑炎国内外研究报道逐渐增多,文中搜集了国内外该类型脑炎的研究现状,并对其临床表现、辅助检查、治疗及预后等研究进展进行综述。

Autoimmune encephalitis(AE) refers to a type of encephalitis caused by the development of autoantibodies against neuronal antigens by the immune system. Anti-gamma-aminobutyric acid-B receptor encephalitis is a rare autoimmune encephalitis associated with anti-neuronal cell surface antibodies. In recent years, reports of anti-gamma-aminobutyric acid-B receptor encephalitis have gradually increased at home and abroad. By collecting the research status of this type of encephalitis at home and abroad, and the clinical manifestations, auxiliary examinations, treatment and prognosis of this type of encephalitis were reviewed.