重庆市315例丙型病毒性肝炎患者临床特征分析

Analysis on clinical features of 315 cases of viral hepatitis C in Chongqing City

目的分析丙型病毒性肝炎(简称“丙肝”)患者的临床特征。方法选取2018年重庆市病例报告数较多的7个区县中报告数较多的9家医院,2019年6月至2020年12月对以上9家医院诊断的18岁及以上全部丙肝抗体阳性病例进行横断面调查,通过问卷调查了解其一般特征、流行病学史、检测发现途径等情况,抽血检测其丙肝核酸情况。结果共调查符合条件的丙肝患者315例,以初中及以下(68.5%)、40~60岁年龄段(68.9%)人群为主。患者过去主要有医源性暴露史(69.5%)及高危行为史(33.1%)。通过各类医疗服务筛查发现的病例有174例(55.2%),就诊者主动要求检测仅有44例(14.0%)。297例(94.3%)丙肝核酸检测阳性。结论重庆市丙肝患者以40~60岁的初中及以下文化程度人群为主,且患者主动检测意识较差,应加强动员检测工作,积极发现并动员患者“应治尽治”。

Objective To analyze the clinical features of the patients with viral hepatitis C.Methods Nine hospitals with more reported cases in Chongqing City from June 2019 to December 2020 were selected.The whole cases of viral hepatitis C antibody positive aged more than 18 years old diagnosed in these 9 hospitals conducted the cross-sectional survey.Their general characteristics,epidemiological history,detection and discovery pathway were understood by the questionnaire survey,and the hepatitis C virus(HCV)nucleic acid was examined by collecting blood.Results A total of 315 cases of viral hepatitis C conforming to the condition were investigated,68.5%of them were junior school education or below,and 68.9%of them were 40-60 years old.69.5%of the patients had the iatrogenic exposure history and 33.1%of the patients had the high-risk behavior history.A total of 174 cases(55.2%)were discovered by various medical service screening,and there were only 44 cases(14.0%)of active examination.The HCV nucleic acid detection was positive in 297 cases(94.3%).Conclusion The patients with viral hepatitis C were mainly the populations aged 40-60 years old and with the cultural level under middle school,moreover the awareness of active examination of the patients were poor,it is necessary to strengthen the mobilization of detection work,and actively discover and mobilize the patients to be treated as much as possible.