孟鲁司特联合布地奈德治疗老年支气管哮喘的临床效果分析

Analysis of the Clinical Effect of Montelukast Combined with Budesonide in the Treatment of Senile Bronchial Asthma

探讨孟鲁司特联合布地奈德治疗老年支气管哮喘的临床疗效,为老年支气管哮喘患者提供科学合理的治疗方法。选取108例支气管哮喘老年患者作为研究对象,随机分为对照组和观察组。对照组采用布地奈德吸入气雾剂经口吸入治疗,观察组在对照组的基础上增加孟鲁司特片口服治疗,患者治疗15d后,比较两组患者第1秒用力呼气容积(FEV1)及第1秒用力呼气容积占用力肺活量百分比(FEV1/FVC)及哮鸣音消失时间、喘息消失时间、咳嗽消失时间和治疗效果满意度及不良反应发生率。结果表明:观察组FEV1和FEV1/FVC均显著高于对照组;临床症状缓解时间显著短于对照组;治疗总有效率显著高于对照组;不良反应发生率显著低于对照组(P<0.05)。经联合治疗的患者肺功能得到了显著改善,加快了病情的康复,患者对治疗效果较为满意。

The study explores the clinical effect of Montelukast combined with Budesonide in the treatment of senile bronchial asthma,to provide scientific and rational treatment method in the treatment of senile bronchial asthma.108 senile patients with bronchial asthma are selected,and they are randomly divided into control group and observation group.Control group receive oral Budesonide inhalation aerosol,and observation receive Montelukast pill oral medication based on observation group.After 15 d treatment,FEV1 in the 1st second,FEV1/FVC in the 1st second,wheezing,gasping and coughing extinction time,treatment effect satisfaction rate and adverse reaction rate of two groups are compared.The results show that FEV1 and FEV1/FVC of observation group are significantly higher than control group.Clinical remission time is significantly shorter than control group,total effective treatment rate is significantly higher than control group,and adverse reaction rate is significantly lower than control group(P<0.05).Lung function of patients through combined treatment has improved significantly.The recovery is sped up,and the patients are satisfied with the treatment effect.