肺腺癌中央区转移瘤的手术治疗

Surgical treatment of lung adenocarcinoma metastasis in the perirolandic region

目的探讨肺腺癌中央区转移瘤手术治疗的可行性。方法选取23例肺腺癌中央区转移瘤手术患者,分析其临床资料、手术结果、术后综合治疗及随访结果。结果23例患者中,22例患者位于中央区的转移瘤全切除,1例患者部分切除。术后1个月肌力好转14例,肌力无变化7例,肌力下降2例;中位总生存期为30.3个月,中位无进展生存期为22.0个月。结论肺腺癌中央区转移瘤可开展手术切除为主的综合治疗。运用多模态影像神经导航等技术有利于保护重要神经功能,多学科综合治疗有利于改善肺腺癌中央区转移瘤预后。

Objective To investigate the feasibility of surgical treatment of lung adenocarcinoma metastasis in the perirolandic region.Method A total of 23 patients with lung adenocarcinoma metastasis in the perirolandic region were selected,and the clinical data,surgical outcomes,postoperative comprehensive treatment and followed up results were analyzed.Result Among 23 patients,22 cases received total resection of metastatic tumor in the perirolandic region,and 1 case received partial resection.One month after operation,muscle strength improved in 14 cases,remained unchanged in 7 cases and decreased in 2 cases;the median overall survival was 30.3 months and the median progression-free survival was 22.0 months.Conclusion Lung adenocarcinoma metastasis in the perirolandic region can be treated by comprehensive therapy based on surgical resection.The use of multimodal imaging and neuronavigation is conducive to protect important neural functions,and multidisciplinary comprehensive therapy is conducive to improve the prognosis of lung adenocarcinoma metastasis in the perirolandic region.