黄体支持对促排卵周期人工授精结局影响的研究进展

Review on the effect of luteal phase support on the outcome of ovulation induction-int rauterine insemination

黄体支持是辅助生殖技术中避免因黄体功能受损对妊娠结局造成不良影响的常用措施。近年关于黄体支持影响促排卵周期人工授精助孕结局的研究进展较多,但关于黄体支持能否改善其助孕结局仍存在一定争议。近年来认为,黄体支持可改善助孕结局,有效提高促性腺激素结合人工授精助孕周期的临床妊娠率及活产率。本文从黄体功能不足的评估、黄体功能不足对妊娠结局的影响、促排卵周期人工授精助孕技术及药物治疗的进展、黄体支持改善促排卵周期人工授精的研究现状等方面做了简要综述。

Luteal phase support(LPS) is a common measure of assisted reproductive technology to reduce adverse pregnancy outcomes caused by impaired luteal function. In recent years, there are many studies on the effect of LPS on the outcome of ovulation induction-intrauterine insemination(OI-IUI), but whether LPS can improve the outcome of artificial insemination is still controversial. It has been found that LPS can improve the clinical pregnancy rate and live birth rate of OI-IUI. This paper reviewed the evaluation of luteal insufficiency and its impact on pregnancy outcome, the progress of OI-IUI technology and drug treatment, and the research status of LPS in improving artificial insemination in ovulation induction cycle.