骨外科患者感染伤口细菌检验及耐药性分析

Bacteria test and drug resistance analysis of infected wounds in patients with orthopedic surgery

目的对骨外科患者感染伤口细菌检验结果进行分析,探究其耐药性。方法选取2018年1月-2021年6月本院370例骨外科伤口感染患者作为研究对象,所有患者均接受感染伤口细菌检验,对细菌检验结果、病原菌类型、耐药性进行分析。结果370例患者中共分离出225株(60.81%)病原菌;排名前3位分别为金黄色葡萄球菌(23.11%)大肠埃希菌(17.78%)、鲍曼不动杆菌(14.67%)。药敏试验结果显示,金黄色葡萄球菌、凝固酶阴性葡萄球菌均对青霉素、氨苄西林、红霉素耐药性高;大肠埃希菌、肺炎克雷伯菌对氨苄西林均具有较高的耐药性,鲍曼不动杆菌铜绿假单胞菌对头孢噻肟、头孢曲松及头孢吡肟耐药性高。结论骨外科患者感染伤口病原菌类型复杂,且耐药问.题严重,应予以高度重视。

Objective To analyze the bacterial test results of infected wounds in orthopedic surgery patients and explore their drug resistance. Methods From January 2018 to June 2021,370 patients with wound infection after orthopedic surgery in our hospital were selected as the research objects. All patients were conducted for the test of bacteria in infected wounds,and the results of bacterial test,pathogen type,and drug resistance were analyzed. Results A total of 225( 60. 81%) pathogens were isolated from 370 patients. The top 3 were Staphylococcus aureus( 23. 11%),Escherichia coli( 17. 78%),and Acinetobacter baumannii( 14. 67%). Sensitivity test results showed that Staphylococcus aureus and coagulase-negative Staphylococcus are highly resistant to penicillin,ampicillin,and erythromycin;Escherichia coli and Klebsiella pneumoniae are highly resistant to ampicillin. Acinetobacter baumannii and Pseudomonas aeruginosa are highly resistant to cefotaxime,ceftriaxone and cefepime.Conclusion In orthopedic surgery patients,the types of pathogenic bacteria in infected wounds are complicated,and the problem of drug resistance is severe,which should be paid more attention to.