摘要
肿瘤转移相关基因(MTA)是与肿瘤进展相关的一个基因家族。MTA1是其主要成员之一,在多种肿瘤中异常表达,与肿瘤的侵袭、转移和预后密切相关,具有重要的临床研究价值。该文对MTA1的结构、功能及其在妇科恶性肿瘤中的研究进展作一综述。
Tumor metastasis-associated gene(MTA)is a gene family related to tumor progression,of which MTA1 is one of the main members.It is abnormally expressed in a variety of tumors,which is closely related to tumor invasion,metastasis and prognosis,and has important clinical research value.This paper reviews the structure and function of MTA1 and its research progress in gynecological malignant tumors.
作者
宋振(综述)
金平(审校)
SONG Zhen;JIN Ping(Department of Gynecology,Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University,Guangdong 518000,China)
出处
《中国临床新医学》
2022年第7期662-665,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
肿瘤转移相关基因1
组蛋白去乙酰化酶
子宫内膜癌
宫颈癌
卵巢癌
Tumor metastasis-associated gene 1(MTA1)
Histone deacetylase
Endometrial cancer
Cervical cancer
Ovarian cancer
