乙型肝炎病毒相关性肝癌的早期诊断与预测模型

Early diagnosis and predictive model for hepatitis B virus-related hepatocellular carcinoma

多数肝癌诊断时已属晚期,病死率高。早期诊断肝癌是改善患者预后的关键。近年来亚洲学者针对慢性乙型肝炎人群总结出一系列肝癌风险评分模型,有助于早期识别高危人群,提高肝癌的早期诊断率。现就危险因素及已开发的早期风险预测模型做简要分析,并综述抗病毒治疗对肝癌风险的影响。

Most hepatocellular carcinoma are diagnosed at an advanced stage and thereby have a high mortality rate.Thus,the key to improving patient prognosis is early diagnosis of hepatocellular carcinoma.In recent years,Asian scholars have summarized a series of hepatocellular carcinoma risk score model for population with chronic hepatitis B,which can help to identify high-risk groups early and improve the early diagnosis rate.This paper briefly analyzes the risk factors and validated risk model for early prediction of hepatitis B virus-related hepatocellular carcinoma,and further reviews the effect of antiviral therapy on the risk of hepatocellular carcinoma.