基于核转录因子-κB信号通路中医药治疗咳嗽变异性哮喘的研究进展

A review on treating cough variant asthma in TCM medicine based on nuclear factor-kappa B signaling pathway

现代研究发现咳嗽变异性哮喘与气道炎症、气道高反应及气道重塑有关。中医药通过调控核转录因子-κB(Nuclear Factor-kappa B,NF-κB)信号通路降低气道高反应,抑制气道炎症和气道重塑治疗咳嗽变异性哮喘,取得显著疗效。文章综述中医药通过调控NF-κB信号通路治疗咳嗽变异性哮喘的研究进展。

Modern studies have found that cough variant asthma is related to airway inflammation, airway hyperresponsiveness and airway remodeling. TCM medicine treated cough variant asthma by regulating the NF-κB signaling pathway to decrease airway hyperresponsiveness, and inhibitsairway inflammation and airway remodeling, and gained obviously clinical effect. In this article, a review on treating cough variant asthma in TCM medicine by regulating NF-κB signaling pathway was given for more reference.