八髎穴隔姜灸联合健脾祛湿方治疗肾虚痰湿型多囊卵巢综合征的临床效果

Clinical efficacy of ginger-partitioned moxibustion at Baliao points plus the Jianpi Qushi prescription on polycystic ovary syndrome due to kidney deficiency and phlegm dampness

目的:探究八髎穴隔姜灸联合健脾祛湿方治疗肾虚痰湿型多囊卵巢综合征的临床效果。方法:选择2020年1月-2021年1月梅州市中医医院收治的多囊卵巢综合征(肾虚痰湿型)患者72例,采用随机数字表法分为西医组(36例,予常规西药)与中医组(36例,予八髎穴隔姜灸联合健脾祛湿方)。比较两组临床疗效,治疗前后性激素、卵巢储备功能及治疗期间不良反应发生情况。结果:中医组总有效率高于西医组,差异有统计学意义(P<0.05);治疗前两组卵泡刺激素、黄体生成素、雄激素水平的差异无统计学意义(P>0.05);治疗后两组卵泡刺激素、黄体生成素、雄激素水平低于治疗前,且中医组低于西医组(P<0.05);治疗前两组抗苗勒管激素、抑制素-B水平的差异无统计学意义(P>0.05),治疗后两组抗苗勒管激素、抑制素-B水平低于治疗前,且中医组低于西医组(P<0.05);两组均未发生严重不良事件。结论:八髎穴隔姜灸联合健脾祛湿方治疗多囊卵巢综合征(肾虚痰湿型)效果优于常规西医治疗,可改善患者性激素、卵巢储备功能,安全性高。

Objective:To explore the clinical efficacy of ginger-separated moxibustion at Baliao points(八髎穴)plus the Jianpi Qushi prescription(健脾祛湿方)on polycystic ovary syndrome(PCOS)with kidney deficiency and phlegm-dampness.Methods:From January 2020 to January 2021,a total of 72 cases were selected and divided into the Western medicine group(36 cases,took conventional Western medicine)and the TCM group(36 cases,took ginger-partitoned moxibustion at Baliao points plus the Jianpi Qushi decoction)by the random number table method.The clinical efficacy,sex hormones,ovarian reserve function before and after treatment and the occurrence of adverse reactions during treatment were compared between the two groups.Results:The total efficiency in the TCM group was higher than that in the Western medicine group(P<0.05);before treatment,there was no significant difference in the levels of follicle-stimulating hormone(FSH),luteinizing hormone(LH),and testosterone(T)between the two groups(P>0.05).After treatment,the levels of FSH,LH,and T in the two groups were lower than before,while in the TCM group was lower than the Western medicine group(P<0.05).There was no significant difference in the levels of anti-mtillerian hormone(AMH)and inhibin-B(INH-B)between the two groups before treatment(P>0.05).After treatment,AMH,INH-B in the two groups were lower than before,and the TCM group was lower than the Western medicine group(P<0.05);no serious adverse events occurred in the two groups.Conclusion:Ginger-partitioned moxibustion plus the Jianpi Qushi decoction at Baliao points is more effective than conventional Western medicine on PCOS(the kidney deficiency and phlegm-dampness type),and can improve the patient’s sex hormones and ovarian reserve function,with high safety.