基于伏邪理论探讨清利泄浊方足浴治疗急性痛风性关节炎的临床观察

Clinical observation on treating acute gouty arthritis with the Qingli Xiezhuo prescription foot bath based on hidden pathogen theory

目的:基于伏邪理论探讨清利泄浊方足浴治疗急性痛风性关节炎的临床疗效。方法:选取120例2019年1月-2020年8月于佛山市中医院就诊的急性痛风性关节炎患者,按照随机数字表法分为观察组和对照组,各60例。对照组予常规护理和治疗,观察组在常规治疗基础上予以清利泄浊方足浴治疗。分析两组治疗前后症状体征评分、超敏C反应蛋白、肿瘤坏死因子-α、白细胞介素-1水平,并评价临床疗效。结果:治疗后,两组症状体征评分均较治疗前降低,且观察组均显著低于对照组(P<0.05);治疗后,两组超敏C反应蛋白、肿瘤坏死因子-α、白细胞介素-1水平均较治疗前降低,且观察组均显著低于对照组(P<0.05);治疗后,观察组临床疗效优于对照组(P<0.05)。结论:清利泄浊方足浴能有效改善急性痛风性关节炎,可能与改善炎症反应有关。

Objective:To explore the clinical efficacy of the Qingli Xiezhuo prescription(清利泄浊方)foot bath on acute gouty arthritis based on hidden pathogen theory.Methods:From January 2019 to August 2020,a total of 120 cases were divided into the observation group and the control group according to the random number table method,with 60 cases in each group.The control group received routine nursing and treatment,and the observation group received the Qingli Xiezhuo prescription foot bath treatment more.Results:After treatment,the symptoms and signs scores in the two groups were lower than those before treatment,and in the observation group was significantly lower than the control group(P<0.05);after treatment,hs-CRP,TNF-α,and IL-1 were all lower,and in the observation group was significantly lower than the control group(P<0.05);after treatment,the clinical efficacy in the observation group were better than the control group(P<0.05).Conclusions:The Qingli Xiezhuo prescription foot bath can effectively improve acute gouty arthritis,which may be related to the amelioration of inflammation.