隔物灸联合丁香吴茱萸等药物穴位贴敷减轻阿奇霉素胃肠道不良反应的效果

Effect of Acupoint Application of Separated Moxibustion Combined with Clove and Evodia Rutaecarpa to Reduce the Adverse Reaction of Azithromycin Gastrointestinal Tract

目的探讨隔物灸联合丁香吴茱萸等药物穴位贴敷减轻阿奇霉素胃肠道不良反应的临床效果。方法以我院于2020年7月至2021年12月接收的200例行阿奇霉素进行呼吸道感染的患者作为研究对象,将200例患者分为对照组(100例)和试验组(100例),分别对其施以阿奇霉素及常规防治法、阿奇霉素联合中药穴位敷贴及隔物灸防治法,分析比较两组患者的胃肠道不适程度、不良反应发生情况、胃肠道持续时间、治疗满意度。结果试验组患者胃肠道无反应例数明显比对照组多,重度反应、轻度反应和轻微反应患者例数明显少于对照组,差异有统计学意义(P<0.05)。本研究所涉及的不良反应有腹痛、呕吐、恶心、腹泻4种。试验组5例患者发生不良反应,发生率为5.00%,对照组20例患者发生不良反应,发生率为20.00%,差异有统计学意义(χ^(2)=10.2857,P<0.05)。试验组发生腹痛、呕吐、恶心、腹泻等不良反应的持续时间明显比对照组短,差异有统计学意义(P<0.05)。试验组满意度为98.00%,明显比对照组的82.00%高(χ^(2)=14.2222,P<0.05)。结论在治疗呼吸道感染过程中,阿奇霉素会引发一系列胃肠道反应,通过中药穴位敷贴及隔物灸对其予以防治,具有显著的治疗效果。在防治过程中,不仅需要控制中药穴位敷贴及隔物灸药饼的大小,还要找准穴位,确保敷贴穴位准确,从而使防治效果得以提高。

Objective To explore the clinical effect of material separated moxibustion combined with acupoint application of drugs such as clove and evodia rutaecarpa to reduce the adverse reaction of azithromycin gastrointestinal tract.Methods Taking 200 patients with respiratory tract infection treated with azithromycin in our hospital from July 2020 to December 2021 as the research object of this subject,the 200 patients were divided into 100 cases of control group and 100 cases of experimental group.Azithromycin and routine prevention and treatment methods,azithromycin combined with traditional Chinese medicine acupoint application and partition moxibustion prevention and treatment methods were applied to them respectively.The degree of gastrointestinal discomfort and adverse reactions of the two groups,duration and treatment satisfaction of gastrointestinal tract were analyzed and compared.Results The number of patients with gastrointestinal non reaction in the experimental group was significantly more than that in the control group,and the number of patients with severe reaction,mild reaction and mild reaction was significantly less than that in the control group(P<0.05).The adverse reactions involved in this study included abdominal pain,vomiting,nausea and diarrhea.The incidence of adverse reactions in 5 patients in the experimental group was 5%,which was significantly lower than that in the control group(20 patients had adverse reactions,the incidence was 20%),the difference was statistically significant(χ^(2)=10.2857,P<0.05).The duration of abdominal pain,vomiting,nausea,diarrhea and other adverse reactions in the experimental group was significantly shorter than that in the control group(P<0.05).The satisfaction of the experimental group was 98.00%,which was significantly higher than 82.00%of the control group(χ^(2)=14.2222,P<0.05).Conclusion Azithromycin can cause a series of gastrointestinal reactions in the treatment of respiratory tract infection.It can be prevented and treated by acupoint application of traditional Chinese medicine and separated moxibustion,which has a significant therapeutic effect.In the process of prevention and treatment,it is not only necessary to control the size of traditional Chinese medicine acupoint application and separated moxibustion cake,but also to find the acupoints to ensure the accuracy of acupoint application,so as to improve the prevention and treatment effect.