持续血液净化在重症监护室中的应用进展

Application progress of continuous blood purification in intensive care unit

严重急性肾功能衰竭(Severe acute renal failure,SARF)发生时,肾功能不全,血液透析或血液滤过成为必要的措施以维持体液平衡.SARF越来越多地与多器官衰竭相关,并已成为重症监护病房的主要疾病.持续性血液净化治疗(continuous blood purification,CBP)在危重病人中有几个优点,包括更大的灵活性、良好的血流动力学耐受性、出色的体液平衡控制、良好的尿毒症控制、脑水肿预防、提供充分和积极营养的能力以及可能的抗炎作用.基于此,此文对近年来CBP在重症监护室(Intensive care unit,ICU)中的临床应用进行了文献复习,重探CBP应用于ICU中的研究进展,以期为今后针对ICU患者合理选取治疗方案提供可靠依据.

When severe acute renal failure(SARF)occurs,renal insufficiency,hernodialysis or hemofilration become necessary to maintain homeostasis.SARF is increasingly associated with multiple organ failure and has become a major disease in intensive care units.Continuous blood purification therapy(CBP)has several advantages in cically ill patients,including greater fexibiiygod hemodynamic tolerance,excellent fluid balance control,good uremia control,brain edema prevention,the ability to provide adequate and active nutrition,and possible anti-inflammatory effects.Based on this,this paper reviews the literature on the clinical application of CBP in intensive care unit(ICU)in recent years,and re explores the research progress of CBP in ICU,in order to provide a reliable basis for the rational selection of treatment schemes for ICU patients in the future.