吸气肌训练对中老年阻塞性睡眠呼吸暂停患者训练效果的Meta分析

Effectiveness of inspiratory muscle training on treatment of middle-aged and elderly patients with obstructive sleep apnea: a Meta-analysis

目的评价吸气肌训练对中老年阻塞性睡眠呼吸暂停(OSA)患者的干预效果。方法计算机检索PubMed、Embase、Cochrane Library、Web of Science、中国知网、中国生物医学文献数据库和万方数据库中关于对中老年OSA患者进行吸气肌训练的随机对照试验,时间为建库至2020年12月,对纳入的文献进行质量评价并提取数据,采用RevMan5.3软件进行Meta分析。结果共纳入8项随机对照试验,Meta分析表明,吸气肌训练能够降低中老年OSA患者的睡眠呼吸暂停低通气指数(AHI)(P<0.05)、Epworth嗜睡量表评分(ESS)(P<0.01)和匹兹堡睡眠质量指数(PSQI)评分(P<0.01),但是对夜间最低血氧饱和度无明显作用(P>0.05)。结论吸气肌训练对中老年OSA患者的AHI、ESS、PSQI有良好的改善效果,是一种安全可行的训练方法。

Objective To evaluate the effectiveness of inspiratory muscle training in middle-aged and elderly patients with obstructive sleep apnea(OSA).Methods The randomized controlled trials(RCT)on the effect of inspiratory muscle training in middle-aged and elderly patients with OSA were collected using the databases of PubMed,Embase,Cochrane Library,Web of Science,Chinese National Knowledge Infrastructure,Chinese Biomedical Literature Database and Wanfang database,the time was from the construction of the database to December 2020.The literature quality was evaluated and data were extracted from the included literature.RevMan5.3 software was used to analyze the collected data.Results A total of 8 RCTs were included.Meta-analysis showed that inspiratory muscle training could reduce apnea hypopnea index(AHI)(P<0.05),Epworth Sleepiness Scale(ESS)(P<0.01)and Pittsburgh Sleep Quality Index(PQSI)(P<0.01),but had no effect on lowest oxygen saturation(P>0.05).Conclusions Inspiratory muscle training is a safe and feasible training method that can decrease AHI,ESS and PSQI in middle-aged and elderly patients with OSA.