鸡滑液支原体灭活疫苗(YBF-MS1株)的临床应用效果

Clinical Application of Chicken Mycoplasma synovial Inactivated Vaccine(YBF-MS1 Strain)

为了解鸡滑液支原体灭活疫苗(YBF-MS1株)的临床应用效果,分别对未免疫和免疫2次YBF-MS1疫苗后种鸡的产蛋率、孵化率、后代呼吸道和腿病发生率以及商品蛋鸡的产蛋下降率和破蛋率进行比对和分析。结果显示:免疫2次YBF-MS1灭活疫苗后,种鸡产蛋率提高1.2%~15.8%,种蛋孵化率提高0~7.3%,后代发病率降低16.7%~75.0%;商品蛋鸡产蛋下降率改善16.7%~100%,破蛋率下降25.0%~100%。结果说明:YBF-MS1灭活疫苗对滑液囊支原体(MS)感染具有较好的保护效果,可显著提高种鸡产蛋率、种蛋孵化率,降低商品代鸡的发病率,同时减少商品蛋鸡顶端异常综合征(EAA)的发生。本研究为科学评价滑液支原体灭活疫苗(YBF-MS1株)的临床应用效果提供了数据支撑。

In order to investigate the effect of clinical application of chicken Mycoplasma synovialis(MS)inactivated vaccine(YBF-MS1strain),the laying rate,hatchability,incidence of respiratory and leg diseases in the offsprings of breeding hens vaccinated with YBF-MS1 vaccine twice and those without vaccination,as well as the reduction rate of laying and shell damage of commercial laying hens were compared and analyzed.The results showed that the laying rate increased by 1.2%-15.8%after the breeding hens were vaccinated with YBF-MS1 inactivated vaccine twice,the hatchability increased by 0-7.3%and the disease incidence of their offsprings decreased by 16.7%-75.0%;the reduction rate of laying was improved by 16.7%-100%and the shell damage reduced by 25.0%-100%.In conclusion,MS infection could be well controlled by YBF-MS1 inactivated vaccine,by which,laying rate and hatching rate were greatly improved,and the incidence rate of commercial generation chickens as well as the incidence of abnormal apical syndrome(EAA)in commercial laying hens were reduced.To this end,future evaluation on clinical application of YBF-MS1 would be supported by the data provided in the study.