肺鳞癌合并肺肉瘤样癌变治疗1例及文献复习

A case report and literature review treatment of squamous cell lung cancer combined with pulmonary sarcomatoid carcinoma

肺鳞癌是非小细胞肺癌中的一种亚型,其特殊的临床病理特点及分子背景决定了其治疗的局限性。肺肉瘤样癌是一种非小细胞肺癌,包含肉瘤或肉瘤样分化的成分,一种由上皮组织和间叶组织混合形成的恶性肿瘤,代表了上皮和间充质分化的整体连续谱系,是一类分化差、临床进展迅速、极少见的肺部恶性肿瘤。二者同时存在较为少见,治疗也较为棘手。结合相关的文献复习,现对贵州医科大学附属人民医院呼吸与危重症医学科近来收治的1例诊断肺鳞癌合并肺肉瘤样癌变的患者相关临床资料进行分析,以期提高临床医生对该疾病的认识。

Squamous cell lung cancer is a unique histological subtype of non-small cell lung cancer,its special clinicopathological features and molecular background determine the limitation of its treatment,pulmonary sarcomatoid canceration is a type of non-small cell lung cancer,contains elements of sarcoma or sarcomatoid differentiation.A malignant tumor of mixed epithelial and mesenchymal tissue,represents a whole continuum of epithelial and mesenchymal differentiation.It is a kind of poorly differentiated lung malignant tumor with rapid clinical progress and rare occurrence.It is rare to have both,treatment is also tricky.Combined with relevant literature review,the clinical data of a patient diagnosed with squamous cell lung cancer complicated with pulmonary sarcomatoid canceration recently admitted to the Department of Respiratory and Critical Medicine of the Affiliated People’s Hospital of Guizhou Medical University were analyzed,in order to improve clinicians’understanding of the disease.