依托咪酯联合纳布啡对腹腔镜下子宫肌瘤剔除术患者麻醉效果的影响

Influence of Etomidate Combined with Nalbuphine on Anesthesia Effect of Patients Undergoing Laparoscopic Myomectomy

目的:探究依托咪酯靶控输注联合纳布啡麻醉对腹腔镜下子宫肌瘤剔除术患者麻醉效果的影响。方法:选取2020年1月-2021年3月广东省佛山市妇幼保健院收治的45例腹腔镜下子宫肌瘤剔除术患者作为研究对象,应用随机数表法分为两组。观察组23例,实行依托咪酯靶控输注联合纳布啡麻醉;参照组22例,实行瑞芬太尼麻醉。比较两组麻醉效果。结果:观察组手术时间、麻醉时间以及苏醒时间均短于参照组,差异具有统计学意义(P<0.05)。参照组不良反应发生率高于观察组,差异具有统计学意义(P<0.05)。结论:在子宫肌瘤剔除术患者手术过程中应用依托咪酯靶控输注联合纳布啡麻醉,可降低不良反应发生率,还可以缩短患者的手术时间、麻醉时间以及苏醒时间,效果显著。

Objective:To explore the influence of etomidate target controlled infusion combined with nalbuphine anesthesia on the anesthesia effect of patients undergoing laparoscopic myomectomy.Methods:A total of 45 patients undergoing laparoscopic myomectomy in Foshan Women and Children Hospital from January 2020 to March 2021 were selected as the study subjects and divided into two groups according to random number table method.The observation group(23 cases)was given etomidate target controlled infusion combined with nalbuphine anesthesia and the reference group(22 cases)was treated with remifentanil anesthesia.The anesthesia effects of two groups were compared.Results:The operation time,anesthesia time and recovery time of the observation group were shorter than those of the reference group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the reference group was higher than that in the observation group,and the difference was statistically significant(P<0.05).Conclusion:Etomidate target controlled infusion combined with nalbuphine anesthesia during the surgery of laparoscopic myomectomy can reduce the incidence of adverse reactions,and shorten the operation time,anesthesia time and recovery time of patients,with significant effects.