聚焦解决模式的认知干预对伴焦虑抑郁的银屑病患者情绪,病耻感及内分泌调节因子的影响

The effects of focusing on solution mode cognitive intervention on adverse emotional reactions,stigma and neuroendocrine regulatory factors in psoriasis patients with anxiety and depression

目的探究聚焦解决模式认知干预辅助治疗对银屑病伴焦虑抑郁患者的疗效。方法选取我科103例银屑病伴焦虑抑郁患者以随机数字表法分组。对照组51例给予常规药物治疗,观察组52例增加聚焦解决模式认知干预心理治疗,对比两组患者不良情绪反应,病耻感,神经内分泌调节因子水平。结果治疗后观察组Beck抑郁自评量表(第2版)(BDI-Ⅱ),汉密尔顿焦虑量表(HAMA),汉密尔顿抑郁量表(HAMD),病耻感内在体验量表(ISMI)和贬低—歧视感知量表(PDD)评分,以及血清神经肽Y(NPY),皮质醇,白介素-2(IL-2)水平均低于对照组(P<0.05)。结论聚焦解决模式认知干预辅助治疗银屑病伴焦虑抑郁患者,可有效改善临床症状,降低焦虑抑郁情绪和病耻感,促进神经内分泌系统恢复。

Objective To explore the efficacy of focused solution mode cognitive intervention in adjutant therapy for psoriasis patients with anxiety and depression.Methods 103 patients with psoriasis with anxiety and depression in our department were divided into groups by random number table method.51 patients in the control group were given conventional drug treatment,and 52 patients in the observation group were given additional psychotherapy with focused solution mode cognitive intervention.The levels of adverse emotional reactions,stigma,and neuroendocrine regulatory factors were compared between the two groups.Results After treatment,the levels of Beck self rating Depression Scale(2nd Edition)(BDI-Ⅱ),Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),stigma intrinsic experience scale(ISMI),demeaning discrimination Perception Scale(PDD),serum neuropeptide Y(NPY),cortisol and interleukin-2(IL-2)in the observation group were lower than those in the control group(P<0.05).Conclusion Focusing on resolving mode cognitive intervention can effectively improve clinical symptoms,reduce anxiety and depression and stigma,and promote neuroendocrine system recovery in psoriasis patients with anxiety and depression.